Publications

2017

  • Alfaro, Jennifer; Pérez de Arce, Felipe; Belmar, Sebastián; Fuentealba, Glenda; Avila, Patricio; Ureta, Gonzalo; Flores, Camila; Acuña, Claudia; Delgado, Luz; Gaete, Diana; Pujala, Brahmam; Barde, Anup; Nayak, Anjan K.; Upendra, T. V. R.; Patel, Dhananjay; et. al. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110 δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies. Journal of Pharmacology and Experimental Therapeutics 361: 312-321 (2017). – See PDF >>
  • Ansari, Amantullah; Satalkar, Sharad; Patil, Varshavekumar; Shete, Amit S.; Kaur, Simranjeet; Gupta, Ashu; Singh, Siddhartha; Raja, Mohd.; Severance, Daniel L.; Bernales, Sebastián; Chakravarty, Sarvajit; Hung, David T.; Pham, Son M.; Herrera, Francisco J.; Rai, Roopa. Novel 3-methylindoline inhibitors of EZH2: Design, synthesis and SAR Bioorganic and Medicinal. Chemistry Letters 27: 217-222 (2017). – See PDF >>
  • Bargsted Leslie, Medinas Danilo B., Martínez Francisca Traub, Rozas Pablo, Muñoz Natalia, Nassif Melissa, Jerez Carolina, Catenaccio Alejandra, Court Felipe A., Hetz Claudio & Matus Soledad. Disulfide cross-linked multimers of TDP-43 and spinal motoneuron loss in a TDP-43A315T ALS/FTD mouse model. Scientific Reports 7: 14266 (2017). – See PDF >>
  • Borgna Vincenzo, Villegas Jaime, Burzio Verónica A., Belmar Sebastián, Araya Mariela, Jeldes Emanuel, Lobos-González Lorena, Silva Verónica, Villota Claudio, Oliveira-Cruz Luciana, Lopez Constanza, Socias Teresa, Castillo Octavio and Burzio Luis O. Mitochondrial ASncmtRNA-1 and ASncmtRNA-2 as potent targets to inhibit tumor growth and metastasis in the RenCa murine renal adenocarcinoma model. Oncotarget, 2017, Vol. 8, (No. 27), pp: 43692-43708. – See PDF >>
  • Candia Enzo, Reyes Paz, Covian Camila, Rodriguez Francisco, Wainstein Nicolas, Morales Jorge, Mosso Claudio, Rosemblatt Mario, Fierro Juan Alberto. Single and combined effect of retinoic acid and rapamycin modulate the generation, activity and homing potential of induced human regulatory T cells. PLoS One 12(7): e0182009 (2017). – See PDF >>
  • Castillo Andrés, Tello Mario, Ringwald Kenneth, Acuña Lillian G., Quatrini Raquel & Orellana Omar. A DNA segment encoding the anticodon stem/loop of tRNA determines the specific recombination of integrative-conjugative elements in Acidithiobacillus species. RNA Biology, 2017. VOL. 0, NO. 0, 1–8. – See PDF >>
  • Castro Matías, Moya-Beltrán Ana, Covarrubias Paulo C., Gonzalez Mónica, Cardenas Juan Pablo, Issotta Francisco, Nuñez Harold, Acuña Lillian G., Encina Gonzalo, Holmes David S., Johnson D. Barrie and Quatrini Raquel. Draft genome sequence of the type strain of the sulfur-oxidizing acidophile, Acidithiobacillus albertensis (DSM 14366). Standards in Genomic Sciences (2017) 12:77. – See PDF >>
  • Castro-Severyn Juan, Remonsellez Francisco, L Valenzuela Sandro, Salinas Cesar, Fortt Jonathan, Aguilar Pablo, Pardo-Esté Coral, Dorador Cristina, Quatrini Raquel, Molina Franck, Aguayo Daniel, Castro-Nallar Eduardo, P Saavedra Claudia. Comparative genomics analysis of a new Exiguobacterium strain from Salar de Huasco reveals a repertoire of stress-related genes and arsenic resistance. Frontiers in Microbiology 8 (2017). – See PDF >>
  • Díaz-Valdivia Natalia I., Calderón Claudia C., Díaz Jorge E., Lobos- González Lorena, Sepulveda Hugo, Ortíz Rina J., Martinez Samuel, Silva Veronica, Maldonado Horacio J., Silva Patricio, Wehinger Sergio, Burzio Verónica A., Torres Vicente A., Montecino Martín, Leyton Lisette and Quest Andrew F.G. Anti-neoplastic drugs increase caveolin-1-dependent migration, invasion and metastasis of cancer cells. Oncotarget, 2017, Vol. 8, (No. 67), pp: 111943-111965. – See PDF >>
  • Dopson, Mark; Holmes, David S.; Lazcano, Marcelo; McCredden, Timothy J.; Bryan, Christopher G.; Mulroney, Kieran T.; Steuart, Robert; Jackaman, Connie; Watkin, Elizabeth L. J. Multiple Osmotic Stress Responses in Acidihalobacter prosperus Result in Tolerance to Chloride Ions. Frontiers in Microbiology 7 (2017). – See PDF >>
  • Elgueta, Daniela; Aymerich, María S.; Contreras, Francisco; Montoya, Andro; Celorrio, Marta; Rojo-Bustamante, Estefanía; Riquelme, Eduardo; González, Hugo; Vásquez, Mónica; Franco, Rafael; Pacheco, Rodrigo. Pharmacologic antagonism of dopamine receptor D3 attenuates neurodegeneration and motor impairment in a mouse model of Parkinson’s disease. Neuropharmacology 113: 110-123 (2017). – See PDF >>
  • Figueroa, Claudio; Gálvez-Cancino, Felipe; Oyarce, Cesar; Contreras, Francisco; Prado, Carolina; Valeria, Catalina; Cruz, Sebastián; Lladser, Alvaro; Pacheco, Rodrigo. Inhibition of dopamine receptor D3 signaling in dendritic cells increases antigen cross-presentation to CD8+ T-cells favoring anti-tumor immunity. Journal of Neuroimmunology 303: 99 (2017). – See PDF >>
  • Gálvez-Cancino, Felipe; Roco, Jonathan; Rojas-Colonelli, Nicole; Flores, Camila; Murgas, Paola; Cruz-Gómez, Sebastián; Oyarce, César; Varas-Godoy, Manuel; Sauma, Daniela; Lladser, Alvaro. A short hairpin RNA-based adjuvant targeting NF-κB repressor IκBα promotes migration of dermal dendritic cells to draining lymph nodes and antitumor CTL responses induced by DNA vaccination. Vaccine 35: 4148-4154 (2017). – See PDF >>
  • Gutierrez-Maldonado, Sebastian E.; Garate, Jose Antonio; Retamal, Maria Jose; Cisternas, Marcelo A.; Volkmann, Ulrich G.; Pérez-Acle, Tomás. Accessing the structural and thermodynamic properties of ultra-thin layers of C32 adsorbed on a SiO 2 surface. Chemical Physics Letters 674: 64 (2017). – See PDF >>
  • Krauskopf Erwin, García Fernanda, Funk Robert. Bibliometric analysis of multi-language veterinary journals. Análise bibliométrica de revistas veterinárias multilíngues. TransInformação, Campinas, 29(3):343-352, set./dez., 2017. – See PDF >>
  • Krauskopf Erwin. Call for Caution in the Use of Bibliometric Data. Journal of the Association for Information Science and Technology 68(8):2029–2032, 2017. – See PDF >>
  • Oyarce Cesar, Cruz-Gomez Sebastián, Galvez-Cancino Felipe, Vargas Pablo, Moreau Hélène D., Diaz-Valdivia Natalia, Diaz Jorge, Salazar-Onfray Flavio A., Pacheco Rodrigo, Lennon-Dumenil Ana Maria, Quest Andrew F. G. and Lladser Alvaro. Caveolin-1 Expression Increases upon Maturation in Dendritic Cells and Promotes Their Migration to Lymph Nodes Thereby Favoring the Induction of CD8+ T Cell Responses. Front. Immunol. 8:1794 (2017). – See PDF >>
  • Lopez, C.; Krauskopf, E; Villota, C; Burzio, L.O; Villegas, J. Cervical cancer, human papillomavirus and vaccines: assessment of the information retrieved from general knowledge websites in Chile. Public Health 148: 19-24 (2017). – See PDF >>
  • Macanas-Pirard, Patricia; Broekhuizen, Richard; González, Alfonso; Oyanadel, Claudia; Ernst, Daniel; García, Patricia; Montecinos, Viviana P.; Court, Felipe; Ocqueteau, Mauricio; Ramirez, Pablo; Nervi, Bruno. Resistance of leukemia cells to cytarabine chemotherapy is mediated by bone marrow stroma, involves cell-surface equilibrative nucleoside transporter-1 removal and correlates with patient outcome. Oncotarget 8: 23073-23086 (2017). – See PDF >>
  • Martin, Alberto J.; Contreras-Riquelme, Sebastián; Dominguez, Calixto; Pérez-Acle, Tomás. LoTo: a graphlet based method for the comparison of local topology between gene regulatory networks. PeerJ 5: e3052 (2017). – See PDF >>
  • Nuñez, Harold; Moya-Beltrán, Ana; Covarrubias, Paulo C.; Issotta, Francisco; Cárdenas, Juan Pablo; González, Mónica; Atavales, Joaquín; Acuña, Lillian G.; Johnson, D. Barrie; Quatrini, Raquel. Molecular Systematics of the Genus Acidithiobacillus: Insights into the Phylogenetic Structure and Diversification of the Taxon. Frontiers in Microbiology 8 (2017). – See PDF >>
  • Pacheco, Rodrigo. Targeting dopamine receptor D3 signalling in inflammation. Oncotarget 8: 7224-7225 (2017). – See PDF >>
  • Pardo, Evelyn; Cárcamo, Claudia; Uribe-San Martín, Reinaldo; Ciampi, Ethel; Segovia-Miranda, Fabián; Curkovic-Peña, Cristobal; Montecino, Fabián; Holmes, Christopher; Tichauer, Juan Enrique; Acuña, Eric; Osorio-Barrios, Francisco; Castro, Marjorie; Cortes, Priscilla; Oyanadel, Claudia; Valenzuela, David M.; et. al. Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early prognostic antibodies in multiple sclerosis. PLoS ONE 12: e0177472 (2017). – See PDF >>
  • Perez-Acle Tomas, Fuenzalida Ignacio, Martin Alberto J.M., Santibañez Rodrigo, Avaria Rodrigo, Bernardin Alejandro, Bustos Alvaro M., Garrido Daniel, Dushoff Jonathan, Liu James H. Stochastic simulation of multiscale complex systems with PISKaS: A rule-based approach. Biochemical and Biophysical Research Communications (2017) 1e10. – See PDF >>
  • Quatrini Raquel, Escudero Lorena V., Moya-Beltrán Ana, Galleguillos Pedro A., Issotta Francisco, Acosta Mauricio, Cárdenas Juan Pablo, Nuñez Harold, Salinas Karina, Holmes David S. and Demergasso Cecilia. Draft genome sequence of Acidithiobacillus thiooxidans CLST isolated from the acidic hypersaline Gorbea salt flat in northern Chile. Standards in Genomic Sciences (2017) 12:84. – See PDF >>
  • Ramachandran, Sreekanth A.; Jadhavar, Pradeep S.; Miglani, Sandeep K.; Singh, Manvendra P.; Kalane, Deepak P.; Agarwal, Anil K.; Sathe, Balaji D.; Mukherjee, Kakoli; Gupta, Ashu; Haldar, Srijan; Raja, Mohd; Singh, Siddhartha; Pham, Son M.; Chakravarty, Sarvajit; Quinn, Kevin; et. al. Design, synthesis and optimization of bis-amide derivatives as CSF1R inhibitors. Bioorganic and Medicinal Chemistry Letters 27: 2153 (2017). – See PDF >>
  • Ramachandran, Sreekanth A.; Jadhavar, Pradeep S.; Singh, Manvendra P.; Sharma, Ankesh; Bagle, Gaurav N.; Quinn, Kevin P.; Wong, Po-yin; Protter, Andrew A.; Rai, Roopa; Pham, Son M.; Lindquist, Jeffrey N. Discovery of pyrazolopyrimidine derivatives as novel inhibitors of ataxia telangiectasia and rad3 related protein (ATR). Bioorganic and Medicinal Chemistry Letters 27: 750 (2017). – See PDF >>
  • Saavedra Francisco, Rivera Carlos, Rivas Elizabeth, Merino Paola, Garrido Daniel, Hernández Sergio, Forné Ignasi, Vassias Isabelle, Gurard-Levin Zachary A., Alfaro Iván E., Imhof Axel, Almouzni Genevieve and Loyola Alejandra. PP32 and SET/TAF-I_ proteins regulate the acetylation of newly synthesized histone H4. Nucleic Acids Research Vol. 45, No. 20. 11700–11710, 2017. – See PDF >>
  • Saez-Aguayo, Susana; Rautengarten, Carsten; Temple, Henry; Sanhueza, Dayan; Ejsmentewicz, Troy; Sandoval-Ibañez, Omar; Doñas, Daniela; Parra-Rojas, Juan Pablo; Ebert, Berit; Lehner, Arnaud; Mollet, Jean-Claude; Dupree, Paul; Scheller, Henrik V.; Heazlewood, Joshua L.; Reyes, Francisca C.; et. al. UUAT1 Is a Golgi-Localized UDP-Uronic Acid Transporter That Modulates the Polysaccharide Composition of Arabidopsis Seed Mucilage. Plant Cell 29: 129-143 (2017). – See PDF >>
  • Sandoval-Bórquez Alejandra, Polakovicova Iva, Carrasco-Véliz Nicolás, Lobos-González Lorena, Riquelme Ismael, Carrasco-Avino Gonzalo, Bizama Carolina, Norero Enrique, Owen Gareth I, Roa Juan C. and Corvalán Alejandro H. MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cáncer. Clinical Epigenetics (2017) 9:114. – See PDF >>
  • Sauma Daniela, Crisóstomo Natalia, Fuentes Camila, Gleisner María Alejandra, Hidalgo Yessia, Fuenzalida María José, Rosemblatt Mario, Bono María Rosa. Adoptive transfer of autoimmune splenic dendritic cells to lupus-prone mice triggers a B lymphocyte humoral response. Immunol Res DOI 10.1007/s12026-017-8936-9 (2017) online. – See PDF >>
  • Valdebenito-Maturana, Braulio; Reyes-Suarez, Jose Antonio; Henriquez, Jaime; Holmes, David S.; Quatrini, Raquel; Pohl, Ehmke; Arenas-Salinas, Mauricio Mutantelec. An In Silico mutation simulation platform for comparative electrostatic potential profiling of proteins. Journal of Computational Chemistry 38: 467-474 (2017). – See PDF >>
  • Vargas, AA.; Cisterna, BA.; Saavedra-Leiva, F.; Urrutia, C.; Cea, LA.; Vielma, AH.; Gutierrez-Maldonado, SE.; Martin, AJ.; Pareja-Barrueto, C.; Escalona, Y.; Schmachtenberg, O.; Lagos, CF.; Perez-Acle, T.; Sáez, JC. On Biophysical Properties and Sensitivity to Gap Junction Blockers of Connexin 39 Hemichannels Expressed in HeLa Cells. Frontiers in Physiology 8 (2017). – See PDF >>
  • Villanelo, F.; Escalona, Y.; Pareja-Barrueto, C.; Garate, J. A.; Skerrett, I. M.; Perez-Acle, T. Accessing gap-junction channel structure-function relationships through molecular modeling and simulations. BMC Cell Biology 18 (2017). – See PDF >>
  • Villegas Jaime, Borgna Vincenzo, Burzio Veronica A. Different cancers, same target? AGING 2017, Vol. 9, No. 8 (2017). – See PDF >>

2016

  • Alarcon V.; Hernandez S.; Rubio L.; Alvarez F.; Flores Y.; Varas-Godoy M; De Ferrari G.V.; Kann M.; Villanueva R.A.; Loyola A. The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state. Scientific Reports 6 (2016). – See PDF >>
  • Albornoz, Amelina; Hoffmann, Anja; Lozach, Pierre-Yves; Tischler, Nicole. Early Bunyavirus-Host Cell Interactions. Viruses 8 (2016). – See PDF >>
  • Almeida AM; Urra, C; Moraga C.; Jego, M; Flores A.; Meisel L.; Gonzalez M; Infante R.; Defilippi, BG; Campos-Vargas, R; Orellana A. Proteomic analysis of a segregant population reveals candidate proteins linked to mealiness in peach. Journal of Proteomics 131: 71 (2016). – See PDF >>
  • Barriga, Gonzalo P.; Villalón-Letelier, Fernando; Márquez, Chantal L.; Bignon, Eduardo A.; Acuña, Rodrigo; Ross, Breyan H.; Monasterio, Octavio; Mardones, Gonzalo A.; Vidal, Simon E.; Tischler, Nicole D.; Beasley, David W.C. Inhibition of the Hantavirus Fusion Process by Predicted Domain III and Stem Peptides from Glycoprotein Gc. PLoS Neglected Tropical Diseases 10 (2016). – See PDF >>
  • Bono, Maria; Tejon, Gabriela; Flores-Santibañez, Felipe; Fernandez, Dominique; Rosemblatt, Mario; Sauma, Daniela. Retinoic Acid as a Modulator of T Cell Immunity. Nutrients 8 (2016). – See PDF >>
  • Calfún C.; Domínguez C.; Pérez-Acle T.; Whitlock K.E. Changes in olfactory receptor expression are correlated with odor exposure during early development in the zebrafish (Danio rerio). Chemical Senses 41: 301 (2016). – See PDF >>
  • Cardenas, Juan P.; Quatrini, Raquel; Holmes, David S. Aerobic Lineage of the Oxidative Stress Response Protein Rubrerythrin Emerged in an Ancient Microaerobic, (Hyper) Thermophilic Environment. Frontiers in Microbiology 7 (2016). – See PDF >>
  • Cárdenas, Juan Pablo; Quatrini, Raquel; Holmes, David S. Genomic and metagenomic challenges and opportunities for bioleaching: a mini-review. Research in Microbiology 167: 529-538 (2016). – See PDF >>
  • Chetty, S; Bhakat, S.; Martin, AJM; Soliman, MES. Multi-drug resistance profile of PR20 HIV-1 protease is attributed to distorted conformational and drug binding landscape: molecular dynamics insights. Journal of Biomolecular Structure and Dynamics 34: 135-151 (2016). – See PDF >>
  • Contreras F.; Prado C; Gonzalez H.; Franz D.; Osorio-Barrios F.; Osorio F.; Ugalde V.; López E.; Elgueta D.; Figueroa A.; Lladser A.; Pacheco R. Dopamine receptor D3 signaling on CD4+ T cells favors Th1-and Th17-mediated immunity. Journal of Immunology 196: 4143-4149 (2016). – See PDF >>
  • Dadlani, K., Lopez, C., Gabler, F., Roa, JC., Villota, C., Lina-Villa, L., Boccardo, E., Bustamante, E., Burzio, V., Burzio, LO. and Villegas Olavarria, J. Assessment of the Expression of Long Noncoding Mitochondrial RNAs (lncmtRNAs) During Cervical Cancer Progression and Cervical Carcinoma. J Cancer Sci Ther 8: 2 (2016). – See PDF >>
  • Doñas, Cristian; Carrasco, Macarena; Fritz, Macarena; Prado, Carolina; Tejón, Gabriela; Osorio-Barrios, Francisco; Manríquez, Valeria; Reyes, Paz; Pacheco, Rodrigo; Bono, María Rosa; Loyola, Alejandra; Rosemblatt, Mario. The histone demethylase inhibitor GSK-J4 limits inflammation through the induction of a tolerogenic phenotype on DCs. Journal of Autoimmunity 75: 105-117 (2016). – See PDF >>
  • English, Niall J.; Garate, José-A. Near-microsecond human aquaporin 4 gating dynamics in static and alternating external electric fields: Non-equilibrium molecular dynamics. Journal of Chemical Physics 145 (2016). – See PDF >>
  • Escalona Y.; Garate J.A.; Araya-Secchi R.; Huynh T.; Zhou R.; Pérez-Acle T. Exploring the Membrane Potential of Simple Dual-Membrane Systems as Models for Gap-Junction Channels. Biophysical Journal 110: 2678-2688 (2016). – See PDF >>
  • Fernández, Dominique; Flores-Santibáñez, Felipe; Neira, Jocelyn; Osorio-Barrios, Francisco; Tejón, Gabriela; Nuñez, Sarah; Hidalgo, Yessia; Fuenzalida, Maria Jose; Meza, Daniel; Ureta, Gonzalo; Lladser, Alvaro; Pacheco, Rodrigo; Acuña-Castillo, Claudio; Guixé, Victoria; Quintana, Francisco J.; et. al. Purinergic Signaling as a Regulator of Th17 Cell Plasticity. PLOS ONE 11 (2016). – See PDF >>
  • Gallagher, Ciara M; Garri, Carolina; Cain, Erica L; Ang, Kenny Kean-Hooi; Wilson, Christopher G; Chen, Steven; Hearn, Brian R; Jaishankar, Priyadarshini; Aranda-Diaz, Andres; Arkin, Michelle R; Renslo, Adam R; Walter, Peter. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. ELIFE 5 (2016). – See PDF >>
  • Garate JA; Perez-Acle, T. From dimers to collective dipoles: Structure and dynamics of methanol/ethanol partition by narrow carbon nanotubes. Journal of Chemical Physics 144: 064105 (2016). – See PDF >>
  • González, Carolina; Lazcano, Marcelo; Valdés, Jorge; Holmes, David S. Bioinformatic Analyses of Unique (Orphan) Core Genes of the Genus Acidithiobacillus: Functional Inferences and Use As Molecular Probes for Genomic and Metagenomic/Transcriptomic Interrogation. Frontiers in Microbiology 7 (2016). – See PDF >>
  • Guardado-Calvo, Pablo; Bignon, Eduardo A.; Stettner, Eva; Jeffers, Scott Allen; Pérez-Vargas, Jimena; Pehau-Arnaudet, Gerard; Tortorici, M. Alejandra; Jestin, Jean-Luc; England, Patrick; Tischler, Nicole D.; Rey, Félix A.; Kuhn, Richard J. Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc. PLOS PATHOGENS 12 (2016). – See PDF >>
  • Hernández S., Jiménez G., Alarcón V., Prieto C., Muñoz F., Riquelme C., Venegas M., Brahm J., Loyola A., Villanueva RA. Replication of a chronic hepatitis B virus genotype F1b construct. Arch Virol 161: 583-594 (2016). – See PDF >>
  • Hossain, Md. Amir; Henríquez-Valencia, Carlos; Gómez-Páez, Marcela; Medina, Joaquín; Orellana, Ariel; Vicente-Carbajosa, Jesús; Zouhar, Jan. Identification of Novel Components of the Unfolded Protein Response in Arabidopsis. Frontiers in Plant Science 7 (2016). – See PDF >>
  • Issotta, Francisco; Galleguillos, Pedro; Moya-Beltran, Ana; Davis-Belmar, Carol; Rautenbach, George; Covarrubias, Paulo; Acosta, Mauricio; Ossandon, Francisco; Contador, Yasna; Holmes, David; Marin, Sabrina A.; Quatrini, Raquel; Demergasso, Cecilia. Draft genome sequence of chloride-tolerant Leptospirillum ferriphilum Sp-Cl from industrial bioleaching operations in northern Chile. Standards in Genomic Sciences 11 (2016). – See PDF >>
  • Jadhavar, Pradeep S. Ramachandran, Sreekanth A. Riquelme, Eduardo. Gupta, Ashu. Quinn, Kevin P. Shivakumar, Devleena. Ray, Soumya. Zende, Dnyaneshwar. Nayak, Anjan K. Miglani, Sandeep K. Sathe, Balaji D. Raja, Mohd. Farias, Olivia. Alfaro, Iva. Targeting prostate cancer with compounds possessing dual activity as androgen receptor antagonists and HDAC6 inhibitors. Bioorganic and Medicinal Chemistry Letters 26: 5222-5228 (2016). – See PDF >>
  • Jorquera, Roddy; Ortiz, Rodrigo; Ossandon, F.; Cárdenas, Juan Pablo; Sepúlveda, Rene; González, Carolina; Holmes, David S. SinEx DB: a database for single exon coding sequences in mammalian genomes. Database: the journal of biological databases and curation (2016). – See PDF >>
  • Ligtenberg MA; Mougiakakos D; Mukhopadhyay, M; Witt, K; Lladser A.; Chmielewski, M; Riet, T; Abken, H; Kiessling R. Coexpressed Catalase Protects Chimeric Antigen Receptor-Redirected T Cells as well as Bystander Cells from Oxidative Stress-Induced Loss of Antitumor Activity. Journal of Immunology 196: 759-766 (2016). – See PDF >>
  • Ligtenberg, M. A.; Witt, K.; Galvez-Cancino, F.; Sette, A.; Lundqvist, A.; Lladser, A.; Kiessling, R. Cripto-1 vaccination elicits protective immunity against metastatic melanoma. OncoImmunology 5 (2016). – See PDF >>
  • Lobos-González, Lorena; Silva, Verónica; Araya, Mariela; Restovic, Franko; Echenique, Javiera; Oliveira-Cruz, Luciana; Fitzpatrick, Christopher; Briones, Macarena; Villegas, Jaime; Villota, Claudio; Vidaurre, Soledad; Borgna, Vincenzo; Socias, Miguel; Valenzuela, Sebastián; López, Constanza; et. al. Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors. Oncotarget 7: 58331-58350 (2016). – See PDF >>
  • Marracino, Paolo; Liberti, Micaela; Trapani, Erika; Burnham, Christian; Avena, Massimiliano; Garate, José-Antonio; Apollonio, Francesca; English, Niall. Human Aquaporin 4 Gating Dynamics under Perpendicularly-Oriented Electric-Field Impulses: A Molecular Dynamics Study. International Journal of Molecular Sciences 17 (2016). – See PDF >>
  • Martin, Alberto J. M.; Dominguez, Calixto; Contreras-Riquelme, Sebastián; Holmes, David S.; Pérez-Acle, Tomás; Virolle, Marie-Joelle. Graphlet Based Metrics for the Comparison of Gene Regulatory Networks. PLOS ONE 11 (2016). – See PDF >>
  • Metz, Claudia; Döger, Remziye; Riquelme, Elizabeth; Cortés, Priscilla; Holmes, Christopher; Shaughnessy, Ronan; Oyanadel, Claudia; Grabowski, Catalina; González, Alfonso; Soza, Andrea. Galectin-8 promotes migration and proliferation and prevents apoptosis in U87 glioblastoma cells. Biological Research 49 (2016). – See PDF >>
  • Moraga-Amaro R., González H., Ugalde V., Donoso-Ramos JP., Quintana-Donoso Q., Lara M., Morales B., Rojas P., Pacheco R., Stehberg J. Dopamine receptor D5 deficiency results in a selective reduction of hippocampal NMDA receptor subunit NR2B expression and impaired memory. Neuropharmacology 13: 222-235 (2016). – See PDF >>
  • Muñoz-Espinoza C.; di Genova A; Correa J.; Silva R.; Maass A.; González-Agüero M.; Orellana A.; Hinrichsen P. Transcriptome profiling of grapevine seedless segregants during berry development reveals candidate genes associated with berry weight. BMC Plant Biology 16 (2016). – See PDF >>
  • Nuñez, H; Covarrubias, PC; Moya-Beltrán, A; Issotta, F; Atavales, J; Acuña, LG; Johnson, DB; Quatrini, R. Detection, identification and typing of Acidithiobacillus species and strains: a review. Research in Microbiology 167: 555 (2016). – See PDF >>
  • Oliva, Harold; Pacheco, Rodrigo; Martinez-Navio, José M; Rodríguez-García, Marta; Naranjo-Gómez, Mar; Climent, Núria; Prado, Carolina; Gil, Cristina; Plana, Montserrat; García, Felipe; Miró, José M; Franco, Rafael; Borras, Francesc E; Navaratnam, Naveenan; Gatell, José M; et. al. Increased expression with differential subcellular location of cytidine deaminase APOBEC3G in human CD4+ T-cell activation and dendritic cell maturation. Immunology and Cell Biology 94: 689-700 (2016). – See PDF >>
  • Orellana, Ariel; Moraga, Carol; Araya, Macarena; Moreno, Adrian. Overview of Nucleotide Sugar Transporter Gene Family Functions Across Multiple Species. Journal of Molecular Biology 428: 3150 (2016). – See PDF >>
  • Pujala, Brahmam; Agarwal, Anil K.; Middya, Sandip; Banerjee, Monali; Surya, Arjun; Nayak, Anjan K.; Gupta, Ashu; Khare, Sweta; Guguloth, Rambabu; Randive, Nitin A.; Shinde, Bharat U.; Thakur, Anamika; Patel, Dhananjay I.; Raja, Mohd.; Green, Michael J.; et. al. Discovery of Pyrazolopyrimidine Derivatives as Novel Dual Inhibitors of BTK and PI3Kδ. ACS Medicinal Chemistry Letters 7: 1161-1166 (2016). – See PDF >>
  • Rai, Roopa; Banerjee, Monali; Wong, Darren H.; McCullagh, Emma; Gupta, Ashu; Tripathi, Shailendra; Riquelme, Eduardo; Jangir, Ramnivas; Yadav, Shyamraj; Raja, Mohd.; Melkani, Pankaj; Dixit, Vikas; Patil, Umesh; Shrivastava, Ritesh; Middya, Sandip; et. al. Temozolomide analogs with improved brain/plasma ratios – Exploring the possibility of enhancing the therapeutic index of temozolomide. Bioorganic and Medicinal Chemistry Letters 26: 5103-5109 (2016). – See PDF >>
  • Rautengarten, Carsten; Ebert, Berit; Liu, Lifeng; Stonebloom, Solomon; Smith-Moritz, Andreia M.; Pauly, Markus; Orellana, Ariel; Scheller, Henrik Vibe; Heazlewood, Joshua L. The Arabidopsis Golgi-localized GDP-L-fucose transporter is required for plant development. Nature Communications 7 (2016). – See PDF >>
  • Rodriguez-Furlán, Cecilia; Salinas-Grenet, Hernán; Sandoval, Omar; Recabarren, Camilo; Arraño-Salinas, Paulina; Soto-Alvear, Sylvana; Orellana, Ariel; Blanco-Herrera, Francisca. The Root Hair Specific SYP123 Regulates the Localization of Cell Wall Components and Contributes to Rizhobacterial Priming of Induced Systemic Resistance. Frontiers in Plant Science 7 (2016). – See PDF >>
  • Simon S.; Skupa P.; Viaene T.; Zwiewka M.; Tejos R.; Klíma P.; Carná M.; Rolcík J.; De Rycke R.; Moreno I.; Dobrev P.I.; Orellana A.; Zažímalová E.; Friml J. PIN6 auxin transporter at endoplasmic reticulum and plasma membrane mediates auxin homeostasis and organogenesis in Arabidopsis. New Phytologist 211: 65-74 (2016). – See PDF >>
  • Temple, Henry; Saez-Aguayo, Susana; Reyes, Francisca C; Orellana, Ariel. The inside and outside: topological issues in plant cell wall biosynthesis and the roles of nucleotide sugar transporters. Glycobiology 26: 913-925 (2016). – See PDF >>
  • Ullrich, Sophie R.; González, Carolina; Poehlein, Anja; Tischler, Judith S.; Daniel, Rolf; Schlömann, Michael; Holmes, David S.; Mühling, Martin. Gene Loss and Horizontal Gene Transfer Contributed to the Genome Evolution of the Extreme Acidophile “Ferrovum”. Frontiers in Microbiology 7 (2016). – See PDF >>
  • Ullrich, SR; Poehlein, A; Tischler, JS; González C; Ossandon FJ; Daniel, R; Holmes DS; Schlomann, M; Mühling, M. Genome Analysis of the Biotechnologically Relevant Acidophilic Iron Oxidising Strain JA12 Indicates Phylogenetic and Metabolic Diversity within the Novel Genus “Ferrovum”. PLoS One 11: e0146832 (2016). – See PDF >>
  • Willensky, Shmuel; Bar-Rogovsky, Hagit; Bignon, Eduardo A.; Tischler, Nicole D.; Modis, Yorgo; Dessau, Moshe; Fremont, Daved H. Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation. PLOS Pathogens 12 (2016). – See PDF >>

2015

  • Acuña R, Bignon E, Mancini R, Lozach PY, Tischler ND. Acidification triggers Andes hantavirus membrane fusion and rearrangement of Gc into a stable post-fusion homotrimer. Journal of General Virology 96, 3192-3197 (2015) – See PDF >>
  • Alfaro IE, Varela-Nallar L, Varas-Godoy M, Inestrosa NC (Bernales S). The ROR2 tyrosine kinase receptor regulates dendritic spine morphogenesis in hippocampal neurons. Mol Cell Neurosci 67, 22-30 (2015) – See PDF >>
  • Blanco-Herrera F, Moreno AA, Tapia R, Reyes F, Araya M, D’Alessio C, Parodi A, Orellana A. The UDP-glucose: glycoprotein glucosyltransferase (UGGT), a key enzyme in ER quality control, plays a significant role in plant growth as well as biotic and abiotic stress in Arabidopsis thaliana. BMC Plant Biology 15, 127 (2015) – See PDF >>
  • Bono MR, Fernández D, Flores F, Rosemblatt M, Sauma D. CD73 and CD39 ectonucleotidases in T cell differentiation: Beyond immunosuppression. FEBS Letters 589, 3454-3460 (2015) – See PDF >>
  • Brennan MJ, Karcz J, Vaughn NR, Woolwine-Cunningham Y, DePriest AD, Escalona Y, Perez-Acle T, Skerrett IM. Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction channels Composed of Connexin32. Journal of Biological Chemistry 290(28), 17074-17084 (2015) – See PDF >>
  • Cárdenas JP, Ortiz R, Norris PR, Watkin E and Holmes DS. Reclassification of “Thiobacillus prosperus” (Huber and Stetter 1989) as Acidihalobacter prosperus sp.nov., a member of the Ectothiorhodospiraceae. Int. J. Syst. Evol. Microbiol. 65(10), 3641-3644 (2015) – See PDF >>
  • Ejsmentewicz T, Balic I, Sanhueza D, Barria R, Meneses C, Orellana A, Prieto H, Defilippi BG, Campos-Vargas R. Comparative study of two table grape varieties with contrasting texture during cold storage. Molecules 20, 3667-3680 (2015) – See PDF >>
  • Escalona Y, Garate JA & Perez-Acle T. Exploring the membrane potential of a simple dual membrane system by using a constant electric field. BMC Bioinformatics 16(Suppl 8), A5 (2015) – See PDF >>
  • Esparza M, Jedlicki E, Dopson M and Holmes DS. Expression and activity of the Calvin-Benson-Bassham cycle transcriptional regulator CbbR from Acidithiobacillus ferrooxidans in Ralstonia eutropha. FEMS Microbiol Lett. 362, fnv108 (2015) – See PDF >>
  • Flores F, Fernández D, Meza D, Tejón G, Vargas L, Varela L, Arredondo S, Guixé V, Rosemblatt M, Bono MR and Sauma D. CD73-mediated adenosine production promotes stem cell-like properties in mouse TC17 cells. Immunology 146(4), 582-594 (2015) – See PDF >>
  • Franz D, Contreras F, González H, Prado C, Elgueta D, Figueroa C and Pacheco R. Dopamine receptors D3 and D5 regulate CD4 +T-cell activation and differentiation by modulating ERK activation and cAMP production. Journal of Neuroimmunology 284, 18-29 (2015) – See PDF >>
  • García IE, Maripillán J, Jara O, Ceriani R, Palacios-Muñoz A, Ramachandran J, Olivero P, Perez-Acle T, González C, Sáez JC, Contreras JE y Martínez AD. Keratitis-ichthyosis-deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43. Journal of Investigative Dermatology 135(5), 1338-1347 (2015) – See PDF >>
  • González H, Contreras F and Pacheco R. Regulation of the neurodegenerative process associated to Parkinson’s disease by CD4+ T-cells. Journal of Neuroimmune Pharmacology 10, 561-575 (2015) – See PDF >>
  • Henriquez-Valencia C, Moreno AA, Sandoval-Ibañez O, Mitina I, Blanco-Herrera F, Cifuentes-Esquivel, N, Orellana A. bZIP17 and bZIP60 regulate the expression of BiP3 and other salt stress responsive genes in a UPR-independent manner in Arabidopsis thaliana. Journal of Cellular Biochemistry 116, 1638-1645 (2015) – See PDF >>
  • Hernández S, Jiménez G, Alarcón V, Prieto C, Muñoz F, Riquelme C, Venegas M, Brahm J, Loyola A and Villanueva RA. Replication of a chronic hepatitis B virus genotype F1b construct. Archives of Virology, 1-12 (2015) – See PDF >>
  • Krauskopf E. More to see on Acta Ophthalmologica. Acta Ophthalmologica 93, 92-93 (2015) – See PDF >>
  • Liljeqvist M, Ossandon FJ, Gonzalez C, Rajan S, Stell A, Valdes J, Holmes DS and Dopson M. Metagenomic Analysis Reveals Adaptations to a Cold Adapted Lifestyle in a Low Temperature Acid Mine Drainage Stream. FEMS Microbiology Ecology 91, 12 (2015) – See PDF >>
  • Mendez AS, Alfaro J, Morales-Soto MA, Dar AC, McCullagh E, Gotthardt K, Li H, Acosta-Alvear D, Sidrauski C, Korennykh AV, Bernales S, Shokat KM and Walter P. Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic. eLife 4, 1-27 (2015) – See PDF >>
  • Möller-Acuña P, Contreras-Riquelme JS, Rojas-Fuentes C, Nuñez-Vivanco G, Alzate-Morales J, Iturriaga-Vásquez P, Arias HR, Reyes-Parada M (Pérez-Acle T.). Similarities between the Binding Sites of SB-206553 at Serotonin Type 2 and Alpha7 Acetylcholine Nicotinic Receptors: Rationale for Its Polypharmacological Profile. PLoS One 10(8), 17 (2015) – See PDF >>
  • Moore C, Tejon G, Fuentes C, Hidalgo Y, Bono MR, Maldonado P, Fernandez R, Wood KJ, Fierro JA, Rosemblatt M, Sauma D and Bushell A. Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection. European Journal of Immunology 45, 452-463 (2015) – See PDF >>
  • Nuñez-Lillo G, Cifuentes-Esquivel A, Troggio M, Micheletti D, Infante R, Campos-Vargas R, Orellana A, Blanco-Herrera F, Meneses C. Identification of candidate genes associated with mealiness and maturity date in peach [Prunus persica (L.) Batsch] using QTL analysis and deep sequencing. Tree Genetics and Genomes 11(4), 86 (2015) – See PDF >>
  • Parra-Rojas J, Moreno AA, Mitina I, Orellana A. The dynamic of the splicing of bZIP60 and the proteins encoded by the spliced and unspliced mRNAs reveals some unique features during the activation of UPR in Arabidopsis thaliana. PLoS One 10, 1-21 (2015) – See PDF >>
  • Rivera C, Saavedra F, Alvarez F, Díaz-Celis C, Ugalde V, Li J, Forné I, Gurard-Levin ZA, Almouzni G, Imhof I and Loyola A. Methylation of histone H3 lysine 9 occurs during translation. Nucleic Acids Research 43, 9097-9106 (2015) – See PDF >>
  • Ruiz P, Maldonado P, Hidalgo Y, Sauma D, Rosemblatt M and Bono MR. Alloreactive Regulatory T Cells Allow the Generation of Mixed Chimerism and Transplant Tolerance. Frontiers in Immunology 6, 596 (2015) – See PDF >>
  • Tejón G, Manríquez V, De Calisto J, Flores F, Hidalgo Y, Crisóstomo N, Fernández D, Sauma D, Mora JR, Bono MR and Rosemblatt M. Vitamin A Impairs the Reprogramming of Tregs into IL-17-Producing Cells during Intestinal Inflammation. Biomed Research Interat 2015, 1-8 (2015) – See PDF >>
  • Ugarte GD, Vargas MF, Medina MA, León P, Necuñir D, Elorza AA, Gutiérrez SE, Moon RT, Loyola A and De Ferrari GV. Wnt signaling induces transcription, spatial proximity and translocation of fusion gene partners in human hematopoietic cells. BLOOD 126, 1785-1789 (2015) – See PDF >>

2014

BOOKS AND BOOK CHAPTERS

  • Gonzalo Hernández, Carlos Jaime Barrios Hernández, Gilberto Díaz, Carlos Garcia Garino, Sergio Nesmachnow, Tomas Perez-Acle, Mario Storti, Mariano Vasquez (Editors). High Performance Computing. First HPCLATAM – CLCAR Latin American Conference CARLA. ISBN 978-3-662-45482-4. Valparaíso, Chile (2014)
  • Quatrini and Johnson (Editors). Acidophiles: Life in extremely acidic environments. Caister Academic Press. UK (2014)
  • Ramón Latorre, Ana María Cárdenas, Adrián G. Palacios, Agustín D. Martínez, Alan Neely, Carlos González, David Naranjo, Danilo González, John Ewer, Juan Carlos Sáez, Kathleen Whitlock, Oliver Schmachtenberg, Pablo Muñoz, Patricio Orio, Ramón Latorre & Tomas Perez-Acle. A Haven for Scientists. Editors, Ramón Latorre et al. Centro Interdisciplinario de Neurociencias de Valparaíso. ISBN: 978-956-9447-00-6. Valparaíso, Chile (2014)
  • Jaime Villegas, Alexis Rivas, Rodolfo Ávila, Vincenzo Borgna, Lorena Lobos-Gonzales, Verónica Burzio, Constanza López, Reynaldo Gómez, Eduardo Landerer, Laura Velarde and L. O. Burzio. Long non coding mitochondrial RNAs as potential targets for diagnosis and therapy of bladder cancer. In: Bladder Cancer: Risk Factors, Emerging Treatment Strategies and Challenges . Chapter 5 (pp 96 – 116). Editors, Samantha Haggerty. Nova Science Publishers, Inc. Hauppauge, NY, USA (2014)

INDEXED JOURNALS

  • S. Vidaurre, C. Fitzpatrick, VA. Burzio, M. Briones, C. Villota, J. Villegas, J. Echenique, L. Oliveira-Cruz, M. Araya, V. Borgna, T. Socías, C. López, R. Ávila and LO. Burzio. Down-regulation of the Antisense Mitochondrial ncRNAs is a Unique Vulnerability of Cancer Cells and a Potential Target for Cancer Therapy. Journal Biological Chemistry 289, 27182-27198 (2014)
  • R. Acuña, N. Cifuentes-Muñoz, ChL. Márquez, M. Bulling, J. Klingström, R. Mancini, PY. Lozach, ND. Tischler. Hantavirus Gn and Gc Glycoproteins Self-Assemble into Virus-Like Particles. Journal of Virology 88(4), 2344–2348 (2014)
  • N. Cifuentes-Muñoz, N. Salazar-Quiroz and ND. Tischler. Hantavirus Gn and Gc Envelope Glycoproteins: Key Structural Units for Virus Cell Entry and Virus Assembly. Viruses 6, 1801-1822 (2014)
  • DR. Cochrane, S. Bernales, BM. Jacobsen, DM. Cittelly, EN. Howe, NC. D’Amato, NS. Spoelstra, SM. Edgerton, A. Jean, J. Guerrero, F. Gómez, S. Medicherla, IE. Alfaro, E. McCullagh, P. Jedlicka, KC. Torkko, AD. Thor, AD. Elias, AA. Protter, JK. Richer. Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide. Breast Cancer Res Jan 22, 16(1):R7 (2014)
  • H. Nuñez, D. Loyola, JP. Cárdenas, DS. Holmes, DB. Johnson, R. Quatrini. Multi Locus Sequence Typing scheme for Acidithiobacillus caldus strain evaluation and differentiation. Research in Microbiology 165, 735-742 (2014)
  • C. González, M. Yanquepe, JP. Cárdenas, J. Valdés, R. Quatrini, DS. Holmes, M. Dopson. Genetic variability of psychrotolerant Acidithiobacillus ferrivorans strains revealed by (meta)genomic analysis. Research in Microbiology 165, 726-734 (2014)
  • M. Dopson, DS. Holmes. Metal resistance in acidophilic microorganisms and its significance for biotechnologies. Appl Microbiol Biotechnol 98, 8133-8144 (2014)
  • M. Arenas-Salinas, S. Ortega-Salazar, F. González-Nilo, E. Pohl, DS. Holmes, R. Quatrini. AFAL: a Web Service for Profiling Amino Acids Surrounding Ligands in Proteins. J Comput Aided Mol Des. 28 1069-1076 (2014)
  • M. Dopson, FJ. Ossandón, L. Lövgren, DS. Holmes. Metal resistance or tolerance? Acidophiles confront high metal loads via both abiotic and biotic mechanisms. Front Microbiol 5, 157 (2014)
  • C. Lefimil, E. Jedlicki, DS. Holmes. a-fur, an antisense RNA gene to fur in the extreme acidophile Acidithiobacillus ferrooxidans. Microbiology 160, 514-524 (2014)
  • M. Lolas, PDT. Valenzuela, R. Tjian, Z. Liu. Charting Brachyury-mediated Developmental Pathways During Early Mouse Embryogenesis. PNAS 111, 4478-4483 (2014)
  • Shmaryahu, M. Carrasco and PDT. Valenzuela. Prediction of Bacterial microRNAs and Possible Targets in Human Cell Transcriptome. Journal of Microbiology Vol. 52, No. 6, 482-489 (2014)
  • Rautengarten, B. Ebert, I. Moreno, H. Temple, T. Herter, B. Link, D. Doñas-Cofré, A. Moreno, S. Sáez-Aguayo, F. Blanco, J.C. Mortimer, A. Schultink, WD Reiter, P. Dupree, M. Pauly, JL. Heazlewood, HV. Scheller, A. Orellana. The Golgi localized bifunctional UDP-rhamnose/UDP-galactose transporter family of Arabidopsis. PNAS 111, 11563-11568 (2014)
  • Di Genova, A. Miyasaka-Almeida, C. Muñoz-Espinoza, P. Vizoso, D. Travisany, C. Moraga, M. Pinto, P. Hinrichsen, A. Orellana, A. Maass. Whole genome comparison between table and wine grapes reveals a comprehensive catalog of structural variants. BMC Plant Biology 14, — (2014)
  • Balic, T. Ejsmentewicz, D. Sanhueza, Ch. Silva, T. Peredo, P. Olmedo, M. Barros, J. Verdonk, R. Paredes, C. Meneses, H. Prieto, A. Orellana, B. Defilippi, R. Campos-Vargas. Biochemical and physiological study of the firmness of table grape berries. Postharvest Biology and Technology 93, 15-23 (2014)
  • H. González and R. Pacheco. T-cell mediated regulation of neuroinflammation involved in neurodegenerative diseases. Journal of Neuroinflammation Vol.11 (nº1), 201 (2014)
  • D. Fernández-Suárez, M. Celorrio, JI. Riezu-Boj, A. Ugarte, R. Pacheco, H. González, J. Oyarzabal, CJ. Hillard, R. Franco and MS. Aymerich. Neuroprotective effect of the monoacylglycerol lipase inhibitor JZL184 in a chronic MPTP mouse model. Neurobiology of Aging Vol.35 (nº11), 2603 (2014)
  • Moraga-Amaro, H. González, R. Pacheco and J. Stehberg. Dopamine receptor D3 deficiency results in chronic depression and anxiety. Behavioural Brain Research Vol 274 (nº1), 186 (2014)
  • H. González, D. Elgueta, A. Montoya and R. Pacheco. Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases. Journal of Neuroimmunology Vol.274 (nº1-2), 1 (2014)
  • R. Pacheco, F. Contreras and M. Zouali. The dopaminergic system in autoimmune diseases. Frontiers in Immunology 5, 117 (2014)
  • Rivera, ZA. Gurard-Levin, G. Almouzni, A. Loyola. Histone lysine methylation and chromatin replication. Biochimica et Biophysica Acta (BBA) – Gene Regulatory Mechanisms, 1839, Issue 12, 1433-1439 (2014)
  • MJ. Retamal, MA. Cisternas, SE. Gutiérrez-Maldonado, T. Pérez-Acle, B. Seifert, M. Busch, P. Huber and UG. Volkmann. Towards bio-silicon interfaces: Formation of an ultra-thin self-hydrated artificial membrane composed of dipalmitoylphosphatidylcholine (DPPC) and chitosan deposited in high vacuum from the gas-phase. Journal of Chemical Physics 141, 104201 –, (2014)
  • F. Abarca, SE. Gutiérrez-Maldonado, P. Parada, P. Martínez, A. Maass, T. Pérez-Acle. Insights on the structure and stability of Licanantase: a trimeric acid-stable coiled-coil lipoprotein from Acidithiobacillus thiooxidans. PeerJ 2:e 457 doi: 10.7717/peerj.457 eCollection (2014)
  • R. Araya-Secchi, T. Pérez-Acle, S. Kang, T. Huynh, A. Bernardin, JA. Gárate, Y. Escalona, A. Martínez, I. García, JC. Sáez, R. Zhou. Characterization of a novel water pocket inside the human Cx26 hemi-channel structure. Biophysical Journal 107(3) 599-612 (2014)
  • JA. Gárate, T. Pérez-Acle, C. Oostenbrink. On the thermodynamics of carbon nanotube single-file water loading: Free energy, Energy and Entropy calculations. Physical Chemistry Chemical Physics 16(11) 5119-28 (2014)
  • S. Bhakat, AJ. Martin, ME. Soliman. An integrated molecular dynamics, principal component analysis and residue interaction network approach reveals the impact of M184V mutation on HIV reverse transcriptase resistance to lamivudine. Molecular Biosystems 10 2215-2228 (2014)

2013

  • J Villegas, K Dadlani, R Avila, C Villota, V Burzio, C Lopez, M Socias, L Zapata and LO. Burzio. The Mitochondrial Antisense ncRNAs are Down-Regulated in Early Cervical Carcinoma. J. Cancer Sci Ther S7. 004. doi:10.4172/1948-5956.S7-004, 1-4 (2013)
  • Lobos-González L, Aguilar L, Diaz J, Diaz N, Urra H, Torres VA, Silva V, Fitzpatrick C, Lladser A, Hoek KS, Leyton L, Quest AF. “E cadherin determines Caveolin 1 tumor suppression or metastasis enhancing function in melanoma cells”. Pigment Cell Melanoma Res 26(4). 555-570 (2013)
  • C. Doñas, M. Fritz, V. Manríquez, G. Tejón, M.R. Bono, M.A. Loyola and M. Rosemblatt. Trichostatin A promotes the generation and suppressive functions of regulatory T cells. Clinical and Developmental Immunology Open Access Article ID 679804. doi.org/10.1155/2013/679804. 1-8 (2013)
  • P Ruiz, P Maldonado, Y Hidalgo, A Gleisner, D Sauma, JJ Saez, S Nuñez, M Rosemblatt and M. Bono. Transplant Tolerance: New Insights and Strategies for Long-Term Allograft Acceptance. Clinical and Developmental Immunology Open Access Article. ID210506 1-15 (2013)
  • Nuñez S, Saez JJ, Fernandez D, Flores-Santibañez F, Alvarez K, Tejon G, Ruiz P, Maldonado P, Hidalgo Y, Manriquez V, Bono MR, Rosemblatt M And Sauma D. Th17 cells contribute to anti-tumor immunity and promote the recruitment of th1 cells to the tumor. Immunology 139. 61-71 (2013)
  • Gleisner MA. Reyes P, Alfaro J, Solanes P, Simon V, Crisostomo N, Sauma D, Rosemblatt M And Bono Mr. Dendritic and stromal cells from the spleen of lupic mice present phenotypic and functional abnormalities Mol Immunol 54. 423-34 (2013)
  • P Michea, P Vargas, MH Donnadieu. M Rosemblatt, MR, G Duménil and V Soumelis. Epithelial control of the human pDC response to extracellular bacteria. Eur. J. Immunol. 43. 1–10 (2013)
  • Acuña, R., Cifuentes-Muñoz, N., Márquez, C.L., Bulling, M., Klingström, J., Mancini, R., Lozach, P.Y., Tischler, N.D. Hantavirus Gn and Gc glycoproteins self-assemble into virus-like particles. Journal of Virology [Epub ahead of print] 2334-2348 (2013)
  • Barriga, G., Martínez, C., Galeno, H., Ferrés, M., Lozach, P.Y., Tischler, N.D. Rapid method for Andes hantavirus titration by flow cytometry. Journal of Virological Methods         193(2) 291-294 (2013)
  • Gupta S, Braun M, Tischler N.D., Stoltz M, Sundström KB, Björkström NK, Ljunggren HG, Klingström J. Hantavirus-infection Confers Resistance to Cytotoxic Lymphocyte-Mediated Apoptosis. PLoS Pathogens PLoS Pathog 9(3):e1003272 1-11 (2013)
  • Blaustein M, Pérez-Munizaga D, Sánchez MA, Urrutia C, Grande A, Risso G, Srebrow A, Alfaro J, Colman-Lerner A. Modulation of the Akt pathway reveals a novel link with PERK/eIF2α, which is relevant during hypoxia. PLoS One 29;8(7)e69668 1-14 (2013)
  • Steele JW, Lachenmayer ML, Ju S, Stock A, Liken J, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, Wang R, Ringe D, Fraser P, Westaway D, St George-Hyslop PH, Szabo P, Relkin NR, Buxbaum JD, Glabe CG, Protter AA, Martins RN, Ehrlich ME, Petsko GA, Yue Z, Gandy S. Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer’s mouse model. Mol Psychiatry. 18(08). 889-97. (2013)
  • Steele JW, Ju S, Lachenmayer ML, Liken J, Stock A, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, Wang R, Ringe D, Protter AA, Martins RN, Ehrlich ME, Yue Z, Petsko GA, Gandy S. Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain. Mol Psychiatry. 18(8) 882-8 (2013)
  • H González, F Contreras, C Prado, D Elgueta, D Franz, S Bernales and R Pacheco. Dopamine receptor D3 expressed on CD4+ T cells favors neurodegeneration of dopaminergic neurons during Parkinson’s disease. J. Immunol. 190(10). 5048-56 (2013)
  • C Prado, S Bernales and R Pacheco. Modulation of T-cell mediated immunity by dopamine receptor d5. Endocr Metab Immune Disord Drug Targets. 13(2). 184-94. (2013)
  • Guerrero J, Alfaro IE, Gómez F, Protter AA, Bernales S. Enzalutamide, an androgen receptor signaling inhibitor, induces tumor regression in a mouse model of castration-resistant prostate cancer. Prostate. 73(12). 1291-305 (2013)
  • Bustamante P, Covarrubias P, Levicán G, Katz A, Tapia P, Holmes DS, Quatrini R, Orellana O. ICEAfe1, an actively excising integrative-conjugative element from the biomining bacterium Acidithiobacillus ferrooxidans. J Mol Microbiol Biotech. 22, 399-407 (2013)
  • Osorio, H., Mangold, S., Denis, Y., Ňancucheo, I., Esparza, M., Johnson, D. B., Bonnefoy, V., Dopson, M. and D. S. Holmes. Anaerobic Sulfur Metabolism Coupled to Dissimilatory Iron Reduction in the Extremophile Acidithiobacillus ferrooxidans. Appl. Environ. Microbiology. 79. 2172-81 (2013)
  • R Sepulveda, R Ortiz and DS. Holmes. Astrogenomics: A Convergence of Disciplines Spawning Inspiration. J. Comput Sci Syst Biol. 6. 4. (2013)
  • Acuña LG, Covarrubias PA, Cárdenas JP, Haristoy JJ, Flores R, Nuñez H, Gonzales M, Riadi G, Shmaryahu A, Valdés J, Dopson M, Rawlings D, Banfield J, Holmes, DS and Quatrini R. Genomic Architecture and Gene Repertoire of the Mobilome of the Extreme Acidophile Acidithiobacillus caldus. PLoS One. 8(11) e78237 (2013)
  • Gamboa MC, Baltierra F, Leon G, Krauskopf E. Drought and salt tolerance of transgenic Arabidopsis by overexpression of the vacuolar pyrophosphatase 1 (EVP1) gene from Eucalyptus globulus. Plant Physiology and Biochemistry. 73. 99-105 (2013)
  • Krauskopf E. Deceivement of the research community through manipulation of the impact factor  . Journal of the American Society for Information Science and Technology. 64. 2403. (2013)
  • Krauskopf E. Letter to the editors. Revista Chilena de Cirugia. 65. 95-96. 2013
  • Krauskopf E. In refererence to WKA Young. Neuro-Oncology. 15(2). 148 (2013)
  • Baltierra F., Krauskopf E. Molecular characterization of a novel Na+/H+ antiporter cDNA from Eucalyptus globulus. Biochemical and Biophysical Research Communications. 430. 535-540 (2013)
  • Krauskopf E. Standardization of the institutional address. Scientometrics. 94. 1313-1315 (2013)
  • Leroch M., Silva E., Shmaryahu A., Coehnen, T., Koppenhöfer, D.,Valenzuela, P.D.T., Hahn, M. Transcriptome profiling of Botrytis cinerea conidial germination reveals upregulation of infection-related genes during the prepeneration stage. Eukaryotic Cell 12. 614-626 (2013)
  • Sandoval M., Luarte, A., Herrera, R., Varas-Godoy M., Santibañez, M. Rubio, F.J., Smit A., Gundelfinger E., Li K., Smalla K. and Wyneken U. The glycolytic enzyme aldolase C is up-regulated in rat forebrain microsomes and in the cerebrospinal fluid after repetitive fluoxetine treatment. Brain Research. 1520. 1-14 (2013)
  • Nilo-Poyanco R, Olivares D, Orellana A, Hinrichsen P, Pinto M. Proteomic analysis of grapevine (Vitis vinifera L.) leaf changes induced by transition to autotrophy and exposure to high light irradiance. Journal of Proteomics. 91. 309-330 (2013)
  • Verde I, Abbott AG, Scalabrin S, Jung S, Shu S, Marroni F, Zhebentyayeva T, Dettori MT, Grimwood J, Cattonaro F, Zuccolo A, Rossini L, Jenkins J, Vendramin E, Meisel LA, Decroocq V, Sosinski B, Prochnik S, Mitros T, Policriti A, Cipriani G, Dondini L, Ficklin S, Goodstein DM, Xuan P, Del Fabbro C, Aramini V, Copetti D, Gonzalez S, Horner DS, Falchi R, Lucas S, Mica E, Maldonado J, Lazzari B, Bielenberg D, Pirona R, Miculan M, Barakat A, Testolin R, Stella A, Tartarini S, Tonutti P, Arús P, Orellana A, Wells C, Main D, Vizzotto G, Silva H, Salamini F, Schmutz J, Morgante M, Rokhsar DS. The high-quality draft genome of peach (Prunus persica) identifies unique patterns of genetic diversity, domestication and genome evolution. Nature Genetics. 45(5) 487-494 (2013)
  • A Di Genova, A Miyasaka, C Muñoz-Espinoza, P Vizoso, D Travisany, C Moraga, M Pinto, P Hinrichsen, A Orellana. Whole genome comparison between table and wine grapes reveals a comprehensive catalog of structural variants. BMC Plant Biology. In press. (2013)
  • Meneses C. and Orellana A. Using Genomics To Improve Fruit Quality. Biological Research. Accepted (2013)
  • González-Agüero M, García-Rojas M, Di Genova A, Correa J, Maass A, Orellana A, Hinrichsen P. Identification of two putative reference genes from grapevine suitable for gene expression analysis in berry and related tissues derived from RNA-Seq data. BMC Genomics. doi: 10.1186/1471-2164-14-878. 14. 878 (2013)
  • Ligtenberg MA, Rojas-Colonelli N, Kiessling R, Lladser A. NF-κB activation during intradermal DNA vaccination is essential for eliciting tumor protective antigen-specific CTL responses. Human Vaccines & Immunotherapeutics Vol 9. 2189-2195 (2013)
  • Reyes D, Salazar L, Espinoza E, Pereda C, Castellón E, Valdevenito R, Huidobro C, Inés Becker M, Lladser A, López MN, Salazar-Onfray F. Tumour cell lysate-loaded dendritic cell vaccine induces biochemical and memory immune response in castration-resistant prostate cancer patients. British Journal of Cancer. Vol 109. 1488-1497 (2013)
  • Lai B, Nagy G, Garate JA, Oostenbrink C. Entropic and Enthalpic Contributions to Stereospecific Ligand Binding from Enhanced Sampling Methods. J Chem Inf Model. 23(4):1205. 23(4):1205 (2013)
  • Reale R, English NJ, Garate JA, Marracino P, Liberti M, Apollonio F. Human aquaporin 4 gating dynamics under and after nanosecond-scale static and alternating electric-field impulses: A molecular dynamics study of field effects and relaxation     . J Chem Phys. 139(20):205101 .139(20):205101 (2013)
  • Molina-Quiroz RC, Loyola DE, Muñoz-Villagrán CM, Quatrini R, Vásquez CC, Pérez-Donoso JM. DNA, Cell Wall and General Oxidative Damage Underlie the Tellurite/Cefotaxime Synergistic Effect in Escherichia coli. PLoS One 8(11) e79499 (2013)
  • H González, D Elgueta, A Montoya, R Pacheco. Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases. J. of Neuroimmunol. (In Press) (2014)
  • Fernández-Suárez D, Celorrio M, Riezu-Boj JI, Ugarte A, Pacheco R, González H, Oyarzabal J, Hillard CJ, Franco R, Aymerich MS. The monoacylglycerol lipase inhibitor JZL184 is neuroprotective and alters glial cell phenotype in the chronic MPTP mouse model. Neurobiol Aging. (In Press). 2014

2012

  • Calisto J., Villablanca E.J., Wang S., Bono M.R., Rosemblatt, M. & Mora J.R. T cell homing to the gut mucosa: General concepts and methodological considerations. In: Integrin And Cell Adhesion Molecules: Methods And Protocols Series 757, 166-189 (2012)
  • Lagos L.X., Iliev D.B., Helland R., Rosemblatt M. & Jorgensen J.B. CD40L – An important Costimulatory molecule involved in the maturation of antigen presenting cells in Atlantic salmon (Salmo salar S.). Developmental and Comparative Immunology 38, 416-430 (2012)
  • Lefimil C., Jedlicki E. & Holmes D.S. An artifact in studies of gene regulation using b-galactosidase reporter gene assays. Anal. Biochem. 421, 333-335 (2012)
  • Moreno A.A., Mukhtar M.S., Blanco F., Boatwright J.L., Moreno I. et al. IRE/bZIP60-Mediated unfolded protein response plays distinct roles in plant immunity and abiotic stress responses. Plos One 7, e31944 (2012)
  • Nilo R., Campos-Vargas R. & Orellana A. Assessment of Prunus persica fruit softening using a proteomics approach. Journal of Proteomics 75, 1618-1638 (2012)
  • Prado C., Contreras F., González H., Díaz P., Elgueta D., Barrientos M., Herrada A.A., Lladser A., Bernales S. & Pacheco R. Stimulation of dopamine receptor D5 expressed in dendritic cells potentiates Th17-mediated immunity. J. Immunol. 188(7), 3062-3070 (2012)
  • Rivas A., Burzio V., Landerer E., Borgna V., Gatica S., Ávila R., López C., Villota C., De la Fuente R., Echenique J., Burzio L.O. & Villegas J. Determination of the differential expression of mitochondrial long non-coding RNAs as a noninvasive diagnosis of bladder cancer. BMC Urology 3 Vol. 12, 37 (2012) Electronic version
  • Sauma D., Ramírez A., Álvarez K., Rosemblatt M. & Bono M.R. Notch signalling regulates cytokine production by CD8+ and CD4+ T cells. Scandinavian Journal of Immunology 75, 389-400 (2012)
  • Villota C., Campos A., Boccardo E., Burzio V.A., Varas M., Villegas J., Villa L.L., Valenzuela P., Socías M., Roberts S. & Burzio L.O. Expression of mitochondrial ncRNAs is modulated by high risk HPV oncogenes*. J. Biological Chemistry 7 287, 21303-21315 (2012)
  • Villota C., Campos A., Vidaurre S., Oliveira L., Bocardo E., Burzio V.A., Varas M., Villegas J., Villa L.L., Valenzuela P.D.T., Socías M., Roberts S. & Burzio L.O. Expression of ncmtRNA is modulated by high risk HPV oncogenes. J. Biol. Chem. In press (2012)

2011

  • Aguayo C., Riquelme J., Urrejola C., Valenzuela PDT. & Silva E. Bchex a virulence gen of Botrytis cinerea: characterization and functional analyses. Journal of General Plant Pathology 77, 230-238 (2011)
  • Álvarez F., Muñoz F., Schilcher P., Imhof A., Almouzni G. & Loyola A. Sequential establishment of marks on soluble histones H3 and H4. Journal of Biological Chemistry 20, 17714-17721 (2011)
  • Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A., Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E., Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Silva E. et al. Genomic analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea. PLOS Genetics 7, 1-27 (2011)
  • Araya-Secchi R.R., Gárate J.A., Holmes D.S. & Pérez-Acle T. Molecular dynamics study of the Archaeal aquaporin AqpM. BMC Genomics 12, S8 (2011)
  • Bonnefoy V. & Holmes, D.S. Genomic insights into microbial iron oxidation and iron homeostasis in extremely acidic environments. Environ. Microbiol. Reports. E. pub. Doi, 10.1111 (2011)
  • Cifuentes-Muñoz N., Barriga G., Valenzuela P.D.T. & Tischler N. Aromatic and polar residues spanning the putative fusion peptide of Andes virus are essential for membrane fusion and infection. Journal of General Virology 92, 552-563 (2011)
  • Gleisner M.A., Rosemblatt M., Fierro J.A. & Bono M.R. Delivery of alloantigens via apoptotic cells generates dendritic cells with an immature tolerogenic phenotype. Transplantation Proceedings 43, 2325-2333 (2011)
  • González Á., Pérez-Acle T., Pardo L. & Deupi X. Molecular basis of ligand dissociation in β-Adrenergic receptors. PLoS One 6, e23815 (2011)
  • González-Nilo F., Pérez-Acle T., Guinez-Molinos S., Geraldo D., Sandoval C., Yévenes A., Santos L.S., Laurie V.F., Mendoza H. & Cachau R.E. Nanoinformatics: an emerging area of information technology at the intersection of bioinformatics, computational chemistry and nanobiotechnology. Biological Research 44, 41-49 (2011)
  • Krauskopf E. The unforeseen impact of meeting abstracts on Cancer Research. Annals of Oncology 22, 2342+ (2011)
  • Lagos C.F., Araya-Secchi R., Thomas P., Pérez-Acle T., Tapia R.A. & Salas, C.O. Molecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathione. Journal Molecular Modeling 2011 Sep 6 [Epub ahead of print] PMID, 21894564 (2011)
  • Landerer L., Villegas J., Burzio V.A., Oliveira L., Villota C., López C., Restovic R., Martínez R., Castillo O. & Burzio L.O. Nuclear localization of the mitocondrial ncRNAs in normal and cancer cells. Cellular Oncology 34, 297-305 (2011)
  • Liljeqvist M., Valdés J., Holmes D.S. & Dopson M. Draft genome of the psychrotolerant acidophile Acidithiobacillus ferrivorans SS3. J Bacteriol. 193, 4304-4305 (2011)
  • Lladser Á., Sanhueza C., Kiessling R. & Quest A.F. Is survivin the potential Achilles’ heel of cancer? Advances in Cancer Research 111, 1-37 (2011)
  • Lladser Á., Mougiakakos D., Tufvesson H., Ligtenberg M.A., Quest A.F., Kiessling R. & Ljungberg K. DAI (DLM-1/ZBP1) as a genetic adjuvant for DNA vaccines that promotes effective antitumor CTL immunity. Molecular Therapy 19, 594-601 (2011)
  • Mangold S., Valdés J., Holmes D.S. & Dopson M. Sulfur metabolism in the extreme acidophile Acidithiobacillus caldus. Front. Microbiol. 2, 17 (2011)
  • Martínez-Navio J.M., Casanova V., Pacheco R., Naval-Macabuhay I., Climent N., García F., Gatell J.M., Mallol J., Gallart T., Lluis C. & Franco R. Adenosine deaminase potentiates the generation of effector, memory and regulatory CD4+ T-cells. Journal of Leukocyte Biology 89, 127-136 (2011)
  • Moore C., Fuentes C., Sauma D., Morales J., Bono M.R., Rosemblatt M. & Fierro J.A. Retinoic acid generates regulatory T cells in experimental transplantation. Transplantation Proceedings 43, 2334-2337 (2011)
  • Moreno A.A. & Orellana A. The physiological role of the unfolded protein response in plants. Biol. Research 44, 75-80 (2011)
  • Sauma D., Espejo P., Ramírez A., Fierro A., Rosemblatt M. & Bono M.R. Differential regulation of Notch ligands in dendritic cells upon interaction with T helper cells. Scand. J. Immunol. 74, 62-70 (2011)
  • Valdés J., Ossandón F., Quatrini R., Dopson M. & Holmes D.S. Draft genome sequence of the extreme acidipohillic biomining proteobacterium Acidithiobacillus thiooxidans ATCC 19377 provides insights into the evolution of the Acidithiobacillus genus. J. Bacteriol. 193(24), 7003 (2011)
  • Vera-Otarola J., Solís L., Soto-Rifo R., Ricci E., Pino K., Tischler N., Ohlmann T., Darlix J.L. & López-Lastra M. The Andes hantavirus NSs protein is expressed from the viral small mRNA by a leaky scanning mechanism. Journal of Virology Accepted (JVI06223-11R1) (2011)
  • Villablanca E.J., Wang S., De Calisto J., Gomes D.C.O., Kane M.A., Napoli J.L., Blaner W.S., Kagechika H., Blomhoff R., Rosemblatt M., Bono M.R., Von Andrian U.H. & Mora J.R. MyD88 and retinoic acid signaling pathways interact to modulate gastrointestinal activities of Dendritic cells. Gastroenterology 141, 176-185 (2011)

2010

  • Busso D., Domínguez C., Pérez-Acle T. & Moreno R. Caspases life-giving: revealing new roles during mouse embryo preimplantation development. Int. J. Dev. Biol. 54, 857-865 (2010)
  • Cárdenas J.P., Valdés J., Quatrini R., Duarte F. & Holmes D.S. Lessons from the genomes of extremely acidophilic bacteria and Archaea with special emphasis on bioleaching microorganisms. Appl. Microbiol. Biotech. 88, 605-620 (2010)
  • Cifuentes-Muñoz N., Darlix J.L. & Tischler N. Development of a lentiviral vector system to study the role of the Andes virus glycoproteins. Virus Res. 153, 29-35 (2010)
  • Engel E.A., Escobar P.F., Rojas L.A., Rivera P.A., Fiore N. & Valenzuela P.D.T. A diagnostic oligonucleotide microarray for simultaneous detection of grapevine viruses. J. Virol. Meth. 163, 445-451 (2010)
  • Engel E.A., Rivera P. & Valenzuela P.D.T. First report of grapevine Syrah Virus-1 in Chilean grapevines. Plant Disease 94, 633 (2010)
  • Engel E.A., Escobar P.F., Rivera P.A. & Valenzuela P.D.T. First report on the occurrence of grapevine leafroll-associated virus 5 in Chilean grapevines. Plant Disease 94(8), 1067 (2010)
  • Esparza M., Cárdenas J.P., Bowien B., Jedlicki E. & Holmes D.S. Genes and pathways for CO2 fixation in the obligate, chemolithoautotrophic acidophile, Acidithiobacillus ferrooxidans. BMC Microbiology 10, 229 (2010)
  • Giorgetti M., Gibbons J.A., Bernales S., Alfaro I.E., Drieu La Rochelle C., Cremers T., Altar C.A., Wronski R., Hutter-Paier B. & Protter A.A. Cognition-enhancing properties of Dimebon in a rat novel object recognition task are unlikely to be associated with acetylcholinesterase inhibition or N-methyl-D-aspartate receptor antagonism. J. Pharmacol. Exp. Ther. 333, 748-757 (2010)
  • Jorgensen T.N., Alfaro J., Enriquez H.L., Jiang C., Loo W.M., Atencio S., Bupp M.R., Mailloux C.M., Metzger T., Flannery S.J., Kotzin B.L., Rosemblatt M., Bono M.R. & Erickson L.D. Development of murine lupus involves the combined genetic contribution of the SLAM and FcgammaR intervals within the Nba2 autoimmune susceptibility locus. J. Immunol. 15, 775-786 (2010)
  • Lanza-Volpe M., Gómez-Talquenca S., Engel E.A. & García O. Incidence of grapevine leafroll associated viruses -1, -2, and -3 in Mendoza vineyards. Tropical Plant Pathology 33, 377-380 (2010)
  • Moore C., Sauma D., Reyes P., Morales J., Rosemblatt M., Bono M.R. & Fierro J.A. Dendritic cells and B cells cooperate in the generation of CD4+CD25+Foxp3+ allogeneic T cells. Transplant. Proc. 42, 371-375 (2010)
  • Muñoz F., Mejía-López J., Pérez-Acle T. & Romero A.H. Uniaxial magnetic anisotropy energy of Fe wires embedded in carbon nanotubes. ACS Nano. 4, 2883-2891 (2010)
  • Nilo R., Saffie C., Lilley K., Baeza-Yates R., Cambiazo V., Campos-Vargas R., González M., Meisel L.A., Retamales J., Silva H. & Orellana A. Proteomic analysis of peach fruit mesocarp softening and chilling injury using difference gel electrophoresis (DIGE). BMC Genomics 11, 43 (2010)
  • Opazo M.C., Figueroa C.R., Henríquez J., Herrera R., Bruno C., Valenzuela P.D.T. & Moya-León M.A. Characterization of two divergent cDNAs encoding xyloglucan endotransglycosylase/hydrolase (XTH) expressed in Fragria chiloensis fruit. Plant Science 179, 479-488 (2010)
  • Pino K., Michea P., Sauma D., Alba A., Morales J., Bono M.R., Fierro A. & Rosemblatt M. Cyclosporin A-treated Dendritic cells may affect the outcome of organ transplantation by decreasing CD4+ CD25+ regulatory T cell. Biol. Res. 43, 333-337 (2010)
  • Reyes F., León G., Donoso M., Brandizzi F., Weber A. & Orellana A. The nucleotide sugar transporters AtUTr1 and AtUTr3 are required for the incorporation of UDP-glucose into the endoplasmic reticulum and are essential for pollen development and needed for embryo sac progress in Arabidopsis thaliana. Plant J. 61, 423-435 (2010)
  • Rivera P.A. & Engel E. Presence of rose spring dwarf-associated virus in Chile: partial genome sequence and detection in roses and their colinizing aphids. Virus Genes 41, 295-297 (2010)
  • Valdés J., Cárdenas J.P., Quatrini R., Esparza M., Osorio H., Duarte F., Lefimil C., Sepúlveda R., Jedlicki E. & Holmes D.S. Comparative genomics begins to unravel the ecophysiology of bioleaching. Hydrometallurgy 104, 471-476 (2010)
  • Wulff-Zottele C., Gatzke N., Kopka J., Orellana A., Hoefgen R., Fisahn J. & Hesse H. Photosynthesis and metabolism interact during acclimation of Arabidopsis thaliana to high irradiance and sulfur depletion. Plant Cell Environ. 33, 1974-1988 (2010)

2009

  • Barría M.I., González A., Vera-Otarola J., León U., Vollrath V., Marsac D., Monasterio O., Pérez-Acle T., Soza A. & López-Lastra M. Analysis of natural variants of the hepatitis C virus internal ribosome entry site reveals that primary sequence plays a key role on cap-independent translation. Nucleic Acids Res. 37, 957-971 (2009)
  • Burzio V.A., Villota C., Villegas J., Landerer E., Boccardo E., Villa L.L., Martínez R., López C., Gaete F., Toro V., Rodríguez X. & Burzio L.O. Expression of a family of non coding mitochondrial rnas distinguishes normal from cancer cells. Proc. Natl. Acad. Sci. USA 106, 430-434 (2009)
  • Cárdenas J.P., Martínez V., Covarrubias P., Holmes D.S. & Quatrini R. Predicting CO/CO2 fixation in Ferroplasma spp. Through a novel chimaeric pathway. Adv. Mat. Res. 71-73, 219-222 (2009)
  • Castro M., Ruiz L., Díaz M., Mamani S., Jerez C.A., Holmes D. & Guiliani N. C-Di-GMP pathway in biomining bacteria. Adv. Mat. Res. 71-73, 223-226 (2009)
  • Duarte F., Araya-Secchi R., González W., Pérez-Acle T., González-Nilo F. & Holmes D.S. Protein function in extremely acidic conditions: molecular simulations of a predicted aquaporin and a potassium channel in Acidithiobacillus ferrooxidans. Advanced Materials Research 71, 211-214 (2009)
  • Elgueta R., Tobar J.A., Shoji K.F., De Calisto J., Kalergis A.M., Bono M.R., Rosemblatt M. & Sáez J.C. Gap junctions at the dendritic cell-Tcell interface are key elements for antigen dependent T-cell activation. J. Immunol. 183, 277-284 (2009)
  • Esparza M., Bowien B., Holmes D.S. & Jedlicki E. Gene organization and CO2-responsive expression of four Cbb operons in Acidithiobacillus ferrooxidans. Adv. Mat. Res. 71-73, 207-210 (2009)
  • Godoy P., Marsac D., Stefas E., Ferrer P., Tischler N.D., Pino K., Ramdohr P., Vial P., Valenzuela P.D.T., Ferrés M., Veas F. & López-Lastra M. Andes virus antigens are shed in urine of patients with acute Hantavirus Cardiopulmonary Syndrome. J. Virol. 83, 5046-5055 (2009)
  • Holmes D.S., Cárdenas J.P., Valdés J., Quatrini R., Esparza M., Osorio H., Duarte F., Lefimil C. & Jedlicki E. Comparative Genomics Begins to Unravel the Ecophysiology of Bioleaching. Adv. Mat. Res. 71-73, 144-150 (2009)
  • Jorgensen T.N., Alfaro J., Henríquez H.L., Loo W.M., Atencio S., Gubbels Bupp M.R., Mailloux C., Metzger T., Flannery S., Ihekweazu C., Rozzo S.S., Kotzin B.L., Rosemblatt M., Bono M.R. & Erickson L.D. Development of murine lupus involves the combined generic contribution of the SLAM and FcgR intervals within the Nba2 susceptibility lucus. J. Immunol. 184, 775-786 (2009)
  • Krauskopf M. & Krauskopf E. Latin American Citation of Revista Médica de Chile –Reply. Revista Médica de Chile 137, 312-314 (2009)
  • Krauskopf E. Making friends in high places? Astronomy & Geophysics 50, 12 (2009)
  • Krauskopf E. Fine tunning assesment of research: The hKA index. Proceedings of ISS. 12th International Conference of ISSI. 2, 1010-1011 (2009)
  • Lefimil C., Osorio H., Quatrini R., Holmes D. & Jedlicki, E. Regulation of expression of the Pet I operon involved in iron oxidation in Acidithiobacillus ferrooxidans. Adv. Mat. Res. 71-73, 199-202 (2009)
  • Levicán G., Katz A., Valdés J., Quatrini R., Holmes D.S. & Orellana O. A 300 Kb genome segment, including a complete set of tRNA genes, is dispensable for Acidithiobacillus ferrooxidans. Adv. Mat. Res. 71-73, 187-190 (2009)
  • Lizama C., Lagos C.F., Lagos-Cabré R., Cantuarias L., Rivera F., Huenchuñir P., Pérez-Acle T., Carrión F. & Moreno R.D. Calpain inhibitors prevent p38 MAPK activation and germ cell apoptosis after heat stress in pubertal rat testes. J Cell Physiol. 221, 296-305 (2009)
  • Loyola A., Tagami H., Bonaldi T., Roche D., Quivy J.P., Imhof A., Nakatani Y., Dent Y.R. & Almouzni G. The HP1α-CAF-1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin. EMBO Report 10, 769-775 (2009)
  • Moore C., Sauma D., Morales J., Bono M.R., Rosemblatt M. & Fierro J.A. Transforming growth factor-b and all-trans retinoic acid generate ex vivo transgenic regulatory T cells with intestinal homing receptors. Transplantation Proceedings 41, 2670-2672 (2009)
  • Müller I., Pinto E., Santibañez M.C., Celedón M.O. & Valenzuela P.D.T. Isolation and characterization of the equine influenza virus causing the 2006 outbreak in Chile. Veterinary Microbiology 137, 172-177 (2009)
  • Nieto P.A., Covarrubias P.C., Jedlicki E., Holmes D.S. & Quatrini R. Selection and evaluation of reference genes for improved interrogation of microbial transcriptomes: case study with the extremophile Acidithiobacillus ferrooxidans. BMC Mol. Biol. 25, 63 (2009)
  • Osorio H., Cárdenas J.P., Valdés J. & Holmes D.S. Prediction of FNR regulated genes and metabolic pathways involved in anaerobic growth of Acidithiobacillus ferrooxidans. Adv. Mat. Res. 71-73, 195-198 (2009)
  • Ossandón F.J., Lazo F., Rivera G. & Holmes D.S. Predicting the function of hypothetical genes in genomes of bioleaching microorganisms. Adv. Mat. Res. 71-73, 203-206 (2009)
  • Pacheco R., Prado C.E., Barrientos M.J. & Bernales S. Role of dopamine in the physiology of T-cells and dendritic cells. J. Neuroimmunol. 30, 1-12 (2009)
  • Quatrini R., Appia-Ayme C., Valdés J., Denis Y., Jedlicki E., Holmes D.S. & Bonnefoy V. Extending the models for iron and sulfur oxidation in the extreme acidophile Acidithiobacillus ferrooxidans. BMC Genomics 10, 394 (2009)
  • Shmaryahu A., Lefimil C., Jedlicki E. & Holmes D.S. Small regulatory RNA genes in Acidithiobacillus ferrooxidans: case studies of 6S RNA and frr. Adv. Mat. Res. 71-73, 191-194 (2009)
  • So A.Y., De la Fuente E., Walter P., Shuman M. & Bernales S. The unfolded protein response during prostate cancer development. Cancer Metastasis Rev. 28, 219-223 (2009)
  • Valdés J.H. & Holmes D.S. Genomic lessons from biomining organisms: Case study of the Acidithiobacillus genus. Adv. Mat. Res. 71-73, 215-218 (2009)
  • Valdés J., Quatrini R., Hallberg K., Mangold S., Dopson M., Valenzuela P.D.T. & Holmes D.S. Draft genome sequence of the extremely acidophilic bacterium Acidithiobacillus caldus ATCC 51756 reveals metabolic versatility in the Acidithiobacillus genus. J. Bacteriol. 191, 5877-5878 (2009)
  • Vizoso P., Meisel L.A., Tittarelli A., Latorre M., Saba J., Caroca R., Maldonado J., Cambiazo V., Campos-Vargas R., González M., Orellana A. & Silva H. Comparative EST transcript profiling of peach fruits under different post-harvest conditions reveals candidate genes associated with peach fruit quality. BMC Genomics. 10, 423 (2009)

2008

  • Artigas R.A., González A., Riquelme E., Carbajal C., Cattani A., Martínez A., Kalergis A. & Pérez-Acle T. A novel Acth receptor (Mc2r) mutation alters its structure and function, causing familial glucocorticoid deficiency. J. Clin Endocrinol Metab. 93(8), 3097-3105 (2008)
  • Colombres M., Gárate J.A., Lagos C.F., Araya-Secchi R., Norambuena P., Quiroz S., Larrondo L., Pérez-Acle T. & Eyzaguirre J. An eleven amino acid residue deletion expands the substrate specificity of acetyl xylan esterase II (AXE II) from Penicillium purpurogenum. J. Comput. Aided Mol. Des. 22(1), 19-28 (2008)
  • Ehrenfeld N., González A., Canon P., Medina C., Pérez-Acle T. & Arce-Johnson P. Structure-function relationship between the tobamovirus TMV-Cg coat protein and the HR-like response. J. Gen. Virol. 89, 809-817 (2008)
  • Elgueta R., Sepúlveda F.E., Vilches F., Vargas L., Mora J.R., Bono M.R. & Rosemblatt M. Imprinting of CCR9 on CD4 T cells requires IL-4 signalling on mesenteric lymph node dendritic cells. J. Immunol. 180, 6501-6507 (2008)
  • Engel E.A., Escobar P., Montt C., Gómez-Talquenca S. & Valenzuela P.D.T. First report on the occurrence of grapevine leafroll-associated virus 7 and 9 in Chilean grapevines. Plant Disease 92(8), 1252-1253 (2008)
  • Engel E.A., Girardi C., Escobar P.F., Arredondo V., Domínguez C., Pérez-Acle T. & Valenzuela P.D.T. Genome analysis and detection of a Chilean isolate of Grapevine leafroll associated virus-3. Virus Genes 37(1), 110-118 (2008)
  • Escobar P.F., Fiore N., Valenzuela P.D.T. & Engel E.A. First detection of grapevine leafroll-associated virus 4 in Chilean grapevines. Plant Disease 92(10), 1474 (2008)
  • Faure-André G.A., Vargas P., Yuseff M.I., Heuzé M., Díaz J., Lankar D., Steri V., Manry J., Hugues S., Vascotto F., Boulanger J., Raposo G., Bono M.R., Rosemblatt M., Piel M. & Lennon-Dumenil A.M. CD74, the MHC class II-associated Invariant Chain, regulates the motility and in vivo migration of dendritic cells. Science 322, 1705-1710 (2008)
  • Goic B., Bustamante J., Miquel A., Alvarez M., Vera M.I., Valenzuela P.D.T. & Burzio L.O. The nucleoprotein and the viral RNA of infectious salmon anemia virus (ISAV) are localized in the nucleolus of infected cells. Virology 379, 55-63 (2008)
  • González-Agüero M., Pavez L., Ibañez F., Pacheco I., Campos-Vargas R., Meisel L.A., Orellana A., Retamales J., Silva H., González M. & Cambiazo V. Identification of woolliness responses genes in peach fruits after postharvest treatments. J. Exp. Bot. 58, 2573-2582 (2008)
  • González A., Sepúlveda L., Araya R., Gárate J.A., Pessoa D., Lagos C. & Pérez-Acle T. Computational modeling study of functional microdomains in cannabinoid receptor type 1. Bioorg. Med. Chem. 16(8), 4378-4389 (2008)
  • Holmes D.S. Review of International Biohydrometallurgy Symposium, Frankfurt, 2007. Hydrometallurgy 92, 69-72 (2008)
  • Krauskopf E. Plant Science research productivity in Chile during the past 20 years. Biol Res. 41, 137-141 (2008)
  • Krauskopf M. & Krauskopf E. Una mirada epistemométrica de la Revista Médica de Chile y su aporte al conocimiento en Medicina. Rev. Méd. Chile 136, 1071-1078 (2008)
  • Lagos C.A., Caballero J., González-Nilo F.D., Pessoa-Mahana D.C & Pérez-Acle T. Docking and Quantitative Structure–Activity Relationship Studies for the Bisphenylbenzimidazole Family of Non- Nucleoside Inhibitors of HIV-1 Reverse Transcriptase. Chem. Biol. Drug Des. 72, 360-369 (2008)
  • Morales J., Bono M.R., Fierro A., Iñiguez R., Zehnder C., Rosemblatt M., Calabran L., Herzog C., Benavente D., Aguiló J., Pefaur J., Alba A., Ferrario M., Simon W., Contreras L. & Buckel E. Alemtuzumab induction in kidney transplantation: clinical results and impact on T-regulatory cells. Transplantation Proceedings 40, 3223-3228 (2008)
  • Moreno I., Norambuena L., Maturana D., Toro M., Vergara C., Orellana A., Zurita-Silva A. & Ordenes V.R. AtHMA1 is a thapsigargin sensitive Ca2+/heavy metal pump. J. Biol. Chem. 283 (15), 9633-9641 (2008)
  • Osorio H., Martínez V., Nieto P.A., Holmes D.S. & Quatrini R. Microbial iron management mechanisms in extremely acidic environments: comparative genomics evidence for diversity and versatility. BMC Microbiology 8, 203 (2008)
  • Osorio H., Martínez V., Veloso F. A., Pedroso I., Valdés J., Jedlicki E., Holmes D. S. & Quatrini R. Iron Homeostasis Strategies in Acidophilic Iron Oxidizers: Studies in Acidithiobacillus and Leptospirillum. Hydrometallurgy 94, 175-179 (2008)
  • Pedroso I., Rivera G., Lazo F., Chacón M., Ossandón F., Veloso F. A. & Holmes D.S. AlterOrf: A database of alternate open reading frames. Nucleic Acid Res. D, 517-518 (2008)
  • Rasmussen-Poblete S., Valdés J., Gamboa M.C., Valenzuela P.D.T. & Krauskopf E. Generation and analysis of an Eucalyptus globulus cDNA library constructed from seedlings subjected to low temperature conditions. Electronic Journal of Biotechnology ISSN, 0717-3458. 11, 2 issue of April 15, (2008)
  • Reyes F. & Orellana A. Golgi transporters: opening the gate to cell wall polysaccharide biosynthesis. Curr. Op. Plant Biol. 11, 244-251 (2008)
  • Stange C., Matus J.T., Domínguez C., Pérez-Acle T. & Arce-Johnson P. The N-homologue LRR domain adopts a folding which explains the TMV-Cg induced HR-like response in sensitive tobacco plants. J. Mol. Graph. Model 26(5), 850-860 (2008)
  • Tischler N.D., Rosemblatt M. & Valenzuela P.D.T. Characterization of cross-reactive and serotype-specific epitopes on the nucleocapsid proteins of hantaviruses. Virus Research. 135, 1-9 (2008)
  • Uribe P., Fuentes D., Valdés J., Shmaryahu A., Zúñiga A., Holmes D. & Valenzuela P.D.T. Preparation and analysis of an expressed sequence Tag library from the toxic dinoflagellate Alexandrium catenella. Marine Biotechnol. 10, 692-700 (2008)
  • Valdés J., Pedroso I., Quatrini R. & Holmes D.S. Comparative genome analysis of Acidithiobacillus ferrooxidans, A. thiooxidans and A. caldus: insights into their metabolism and ecophysiology. Hydrometallurgy 94, 180-184 (2008)
  • Valdés J., Pedroso I., Quatrini R., Tettelin H., Eisen J.A. & Holmes D.S. Acidithiobacillus ferrooxidans metabolism: From genome sequence to industrial applications. BMC Genomics 9, 597 (2008)