Seminar: “The impact of specific dietary molecules on neurodegeneration and behavior”

24/01/2017

Abstract:
We study the specific components of diet that impact a phenotypic outcome (neuronal protection) and change behavioral decisions to ensure an animal’s survival. As model of study, we use the bacterivore nematode C. elegans and its different bacterial diets. We have shown that specific small RNAs are transgenerationally transmitted to communicate the nature of a bacterial source; and found specific enzymes in bacteria that trigger neuronal protection in the worm. This allows us to mechanistically dissect how and when molecules from the nematode’s microbiome cause changes in its physiology and propose informed therapeutical interventions in more complex organisms.

Speaker:
Andrea Calixto, PhD
Assistant Professor
Laboratorio de Neurobiología del Comportamiento
Centro de Genómica y Bioinformática Universidad Mayor
Centro Interdisciplinario de Neurociencia de Valparaíso

Date:
Wednesday, January 25th, 2017

Time:
11:00

Location:
3rd Floor
Fundación Ciencia & Vida
Avenida Zañartu 1482, Ñuñoa, Santiago

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