Carlos Lagos, PhD

Associate Researcher

Chemical Biology & Drug Discovery Lab

Dr. Carlos F. Lagos is a Pharmaceutical Chemist (Pontificia Universidad Católica de Chile, 2008) and holds a Ph.D. in Biotechnology from Universidad Nacional Andrés Bello (2016, Summa Cum Laude). He is Associate Professor at the School of Chemistry and Pharmacy, Universidad San Sebastián, where he leads the Chemical Biology & Drug Discovery Laboratory (CBD2), and Associate Researcher at the Excellence Center Fundación Ciencia & Vida.

His research integrates structural bioinformatics, medicinal chemistry, and molecular pharmacology to identify bioactive molecules targeting metabolic, neurodegenerative, and inflammatory disorders. Current projects focus on nuclear receptor modulation in obesity, multi-target serotonergic ligands for neurodevelopmental disorders, and selective connexin hemichannel modulators with translational potential in epilepsy.

Dr. Lagos has authored over 65 peer-reviewed publications, two book chapters, and is co-inventor on six granted international patents and thirteen additional filings. His work has been recognized with the UC Technology Transfer Award and multiple distinctions from the Endocrine Society and Pontificia Universidad Católica de Chile.

He actively contributes to graduate training, supervising theses in drug discovery and translational pharmacology, and participates in doctoral and master’s programs in Cell Biology, Biomedicine, and Computational Biology.

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Grants

"FONDEF IDeA I+D ID25I10016 Novedosa Aproximación para el Tratamiento contra la Fibrosis: Desarrollo y Evaluación de Nuevos Péptidos Inhibidores del Factor de Crecimiento Pro-Fibrótico de Tejido Conectivo (CTGF) (01/08/2025-31/07/2027), Director: Dr. Enrique Brandan; Investigador: Dr. Carlos F. Lagos Centro Basal Ciencia & Vida, FB210008, Financiamiento Basal para Centros Científicos y Tecnológicos de Excelencia de ANID. (08/11/2021-07/11/2031), Director: Dr. Alvaro Lladser Investigador Asociado Dr. Carlos F. Lagos FONDECYT REGULAR 1241969 Targeting the Mineralocorticoid Receptor Activation as a Novel Approach for Obesity and Metabolic Syndrome (01/04/2024-01/04/2028), IR: Dr Carlos Lagos, Co-I: Alejandro Amoroso (USS), Andrea Vecchiola & Gonzalo Recabarren (PUC) FONDECYT REGULAR 1241192 Discovery of Novel Multi Targeted Serotonergic Ligands: An Interdisciplinary Approach towards Candidates directed to Social and Cognitive Symptomathic Domains of Neurodevelopmental Diseases (01/04/2024-01/04/2028), IR: Dr. Gonzalo Recabarren (PUC), Co-I: Carlos Lagos (USS), Andrea del Campo & José Tomás Egaña (PUC)"

Collaborations

Selected Publications

Featured Publications presents a curated selection of the researcher’s most significant scientific contributions, reflecting their expertise, findings, and the broader impact of their work in advancing knowledge within their field.