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Research & Development

Research & Development

Promoting discovery through advanced scientific research

Centro Ciencia & Vida is one of Chile’s leading hubs for science, bringing together over 120 researchers united by the goal of expanding knowledge and driving innovation. Their work spans three main fields—Biomedicine, Computational Biology, and Microbiology—which are developed in five collaborative clusters. By organizing research in this way, CCV nurtures both scientific excellence and collaboration at the service of people.

Clusters

The five clusters focus on high-impact diseases (autoimmunity, infections, cancer, and neurodegenerative disorders) and strategic areas such as pandemic preparedness and biomining.


This synergistic structure translates world-class discoveries into technologies and advanced human capital, positioning Chile as a competitive hub for biomedical innovation and talent. 

Immune Intervention and Inflammation

  • Mechanism of autoimmunity.

  • Epigenetics & autoimmunity.

Viruses, Microbes and Infections

  • Molecular basis of infection by human viral  pathogens.

  • Role of chromatin modification, histone-like  proteins and membrane fusion proteins in viruses  and mobile genetic elements.

  • Role of gut microbiota in the inflammatory  behavior of autoreactive lymphocytes and in  intestinal homeostasis and perturbation.

Cell Regulation and Tumor biology

  • Protein trafficking, signaling and cell plasticity in cancer.

  • Genetics, epigenetics, and cancer therapy.

  • Antitumor immunity and Immunotherapy.

Cell Signaling and Neuropathology

  • Stress and synaptic homeostasis.

  • Synaptic mitochondrial dysfunction, accumulation of abnormal proteins and protein  degradation in the mitochondria during  neurodegeneration and aging.

  • Antibody-driven brain function.

  • Adaptive immunoreceptors and Parkinson disease.

  • Fibrosis in skeletal muscle diseases.

Modeling and Computational Biology

  • Complex networks, neuromorphic computing.

  • Biophysics of macromolecules.

  • Evolutionary and functional genomics of  extremophiles.

Laboratories

At Centro Ciencia & Vida, laboratory teams investigate biomedicine, microbiology, and computational biology through end-to-end workflows. 
Standardized SOPs, quality controls, and technology transfer pipelines ensure reproducible science that translates into diagnostics, therapies, and biotech innovations.

Publications

Explore peer-reviewed publications across our five research clusters, reflecting international collaboration and translational impact. Indexed outputs have met or exceeded annual targets, and citation rates have risen above projections.
Together, these publications showcase the synergy across clusters and the CCV's progression from foundational discovery to application. 

Apr 4, 2026

MAL33 drives natural variation in maltose metabolism in Saccharomyces eubayanus
MAL33 drives natural variation in maltose metabolism in Saccharomyces eubayanus

Mar 31, 2026

Lymphodepleting preconditioning impairs host antitumor immunity induced by adoptive T cell therapy in mouse models
Lymphodepleting preconditioning impairs host antitumor immunity induced by adoptive T cell therapy in mouse models

Mar 19, 2026

Nanostructured Lipid Carriers as Physicochemical Modulators of Complex Natural Extracts: Release Behavior and Bile-Induced Remodeling in Biorelevant Media
Nanostructured Lipid Carriers as Physicochemical Modulators of Complex Natural Extracts: Release Behavior and Bile-Induced Remodeling in Biorelevant Media

Mar 3, 2026

Unveiling the viral frontier in a warming world: temperature as a key ecological driver of viral diversity in subantarctic Chilean Patagonia fjords
Unveiling the viral frontier in a warming world: temperature as a key ecological driver of viral diversity in subantarctic Chilean Patagonia fjords

Feb 24, 2026

Contrasting functions of CD73 and adenosine in CD8+ T-cell exhaustion during antitumor immunity
Contrasting functions of CD73 and adenosine in CD8+ T-cell exhaustion during antitumor immunity

Jan 31, 2026

Regional consistency in microbial community responses to hydrocarbon pollution in maritime Antarctic soils
Regional consistency in microbial community responses to hydrocarbon pollution in maritime Antarctic soils

In Numbers

Annual Achivements

120

Researchers 

 24

Labs

 127

ISI Publications

 2

Grants
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