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Research & Development

Research & Development

Promoting discovery through advanced scientific research

Centro Ciencia & Vida is one of Chile’s leading hubs for science, bringing together over 120 researchers united by the goal of expanding knowledge and driving innovation. Their work spans three main fields—Biomedicine, Computational Biology, and Microbiology—which are developed in five collaborative clusters. By organizing research in this way, CCV nurtures both scientific excellence and collaboration at the service of people.

Clusters

The five clusters focus on high-impact diseases (autoimmunity, infections, cancer, and neurodegenerative disorders) and strategic areas such as pandemic preparedness and biomining.


This synergistic structure translates world-class discoveries into technologies and advanced human capital, positioning Chile as a competitive hub for biomedical innovation and talent. 

Immune Intervention and Inflammation

  • Immune processes leading to autoimmune disorders.

  • Epigenetics & autoimmunity.

Viruses, Microbes and Infections

  • Molecular bases of infection by human viral pathogens.

  • Gut microbiota & autoreactive lymphocytes.

  • Chromatin modification in viruses and mobile genetic elements.

  • Gut microbiota & inflammation.

Cell Regulation and Tumor biology

  • Protein trafficking, signaling and cell plasticity in cancer.

  • Antitumor immunity and immune therapy.

  • Genetic and epigenetic cancer therapy.

Cell Signaling and Neuropathology

  • Stress and synaptic homeostasis.

  • Synaptic mitochondrial dysfunction in neurodegeneration and aging.

  • Antibody driven brain function.

  • Immunoreceptor and Parkinson's disease.

  • Fibrosis and muscle diseases.

Modeling and Computational Biology

  • Biophysics and macromolecules.

  • Artificial intelligence and neuromorphic computing.

  • Massive data science and complex biological networks.

  • Population structure and dynamics.

Laboratories

At Centro Ciencia & Vida, laboratory teams investigate biomedicine, microbiology, and computational biology through end-to-end workflows. 
Standardized SOPs, quality controls, and technology transfer pipelines ensure reproducible science that translates into diagnostics, therapies, and biotech innovations.

Publications

Explore peer-reviewed publications across our five research clusters, reflecting international collaboration and translational impact. Indexed outputs have met or exceeded annual targets, and citation rates have risen above projections.
Together, these publications showcase the synergy across clusters and the CCV's progression from foundational discovery to application. 

Nov 7, 2025

From Transporter to Motor: Evolutionary and Structural Insights 2 into the Emergence of Prestin’s Area-Motor Activity in Mammals
From Transporter to Motor: Evolutionary and Structural Insights 2 into the Emergence of Prestin’s Area-Motor Activity in Mammals

Aug 26, 2025

Plasma extracellular vesicle surface-located GAS6/ PROS1 and CD39/CD73 attenuate inflammation
Plasma extracellular vesicle surface-located GAS6/ PROS1 and CD39/CD73 attenuate inflammation

Jul 21, 2025

KDELR: Beyond protein retrieval, a novel regulator in cancer progression
KDELR: Beyond protein retrieval, a novel regulator in cancer progression

Jul 15, 2025

Peripheral administration of blood from tau transgenic animals exacerbates brain tau-associated pathology
Peripheral administration of blood from tau transgenic animals exacerbates brain tau-associated pathology

Jul 7, 2025

Helicobacter pylori infection promotes the formation of the β-catenin/HIF-1α complex, enabling adaptive responses in gastric cancer cells
Helicobacter pylori infection promotes the formation of the β-catenin/HIF-1α complex, enabling adaptive responses in gastric cancer cells

Jun 20, 2025

Proper pandemic preparedness requires an integrated cross‐regional efort, the case of the ECLIPSE consortium in America: a narrative review
Proper pandemic preparedness requires an integrated cross‐regional efort, the case of the ECLIPSE consortium in America: a narrative review

In Numbers

Annual Achivements

120

Researchers 

 24

Labs

 127

ISI Publications

 2

Grants
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