Cluster IV
Cell Signaling and Neuropathology
Understanding the various cellular and molecular processes underlying pathologies that affect the central nervous system (CNS) is critical to advance in the identification of therapeutic opportunities for neurodegenerative disorders. This cluster is dedicated to studying complex biological processes behind neuropathologies by focusing on cell signaling pathways that respond to stress and signaling pathways that drive fibrosis as possible new therapeutic targets for diseases affecting the CNS and innervated skeletal muscle.
Research Lines
Stress responses and synaptic homeostasis
How signal transduction pathways driving cell homeostasis are involved in neuronal proteostatis.
Effects of antibodies on brain function
Uncover how pathogenic antibodies associated with brain disorders affect synaptic transmission.
Adaptive immunoreceptors and Parkinson's disease
Role of adaptive signal transduction pathways in synaptic maturation and maintenance.
Fibrosis in skeletal muscle diseases
Inflammation as a critical regulator of regeneration and the fibrotic response in muscle.
Researchers
Latest Publications Cluster IV
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