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At present, there is no clear evidence of the origin and conditions leading to autoimmune diseases. The main focus of this cluster is on the immune response, with an ultimate view on how its manipulation under several conditions could bring about therapeutic approaches. We will join forces to deepen our understanding of the immune processes leading to autoimmune disorders in Parkinson’s disease, lupus, and multiple sclerosis (MS).
Research Lines
Mechanism of autoimmunity
Studies to deepen our understanding of the immune processes that lead to autoimmune disorders.
Epigenetics and autoimmunity
Studies on the mechanism of how the stability of lymphocytes is controlled by epigenetic changes in promoter genes encoding master transcription factors.
Researchers
Latest Publications Cluster I
December 30, 2025
Unraveling sex differences in age-related hippocampal decline: differential mitochondrial dysfunction, Lonp1-dependent mitochondrial proteostasis and mtROS production in aged C57BL/6 mice
October 16, 2025
The Heteromeric Dopamine Receptor D2:D3 Controls the Gut Recruitment and Suppressive Activity of Regulatory T-Cells
October 16, 2025
Immunoregulatory functions of the endoplasmic reticulum stress sensor inositol-requiring enzyme 1 in myeloid cell biology
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