At present, there is no clear evidence of the origin and conditions leading to autoimmune diseases. The main focus of this cluster is on the immune response, with an ultimate view on how its manipulation under several conditions could bring about therapeutic approaches. We will join forces to deepen our understanding of the immune processes leading to autoimmune disorders in Parkinson’s disease, lupus, and multiple sclerosis (MS).
Research Lines
Mechanism of autoimmunity
Studies to deepen our understanding of the immune processes that lead to autoimmune disorders.
Epigenetics and autoimmunity
Studies on the mechanism of how the stability of lymphocytes is controlled by epigenetic changes in promoter genes encoding master transcription factors.
Researchers
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Sarah Nuñez, PhD
Associate Researcher
Fabiola Osorio, PhD
Associate Researcher
Carolina Prado, PhD
Associate Researcher
Micaela Ricca
Associate Researcher
Sebastián Valenzuela
Associate Researcher
Latest Publications Cluster I
Renal antigen-presenting cells from ANG II hypertensive donors transfer blood pressure and promote sodium retention
Patricio Araos,; Pablo León; Ignacio Gallegos-Pérez; Carolina Schäfer; Richard García- Betancourt; Edison Salas-Huenuleo; Carolina Prado; Víctor Barrientos; Jessica Liberona; Tomohiro Kojimahara; Stefanny M. Figueroa; Cristián A. Amador; Leandro J. Carreño; Marcelo J. Kogan; Alexis A. Gonzale; Rodrigo Pacheco; Rodrigo Alzamora,; Heddwen L Brooks; Luis Michea