Enrique Brandan
Principal Investigator
Cell Differentiation and Pathology Lab
Dr. Enrique Brandan earned his degree in Biology from Universidad de Chile in 1978 and a PhD in Cell Biology from Pontificia Universidad Católica de Chile in 1985. He conducted postdoctoral training in the United States at Saint Louis University and the University of Massachusetts.
In 1988, he joined the Faculty of Biological Sciences at Pontificia Universidad Católica de Chile, where he became Full Professor in 1999. Since 2019, he has been part of Fundación Ciencia & Vida.
Dr. Brandan is a member of the Chilean Academy of Sciences (2007) and the Latin American Academy of Sciences (2017). He was an International Research Scholar of the Howard Hughes Medical Institute (1997–2006) and received the Chilean Presidential Chair in Sciences (1998–2001). His research has been supported by international and national institutions, including MDA, HHMI, NSF, Fogarty International, TWAS, Volkswagen-Stiftung, IFS, and ANID (formerly CONICYT).
He served as President of the Chilean Society for Cell Biology and held leadership roles at Pontificia Universidad Católica de Chile, including Chair of the Cellular and Molecular Biology Department. Students have recognized his teaching by naming him "Best Teacher" twice, and he has mentored more than 40 graduate and undergraduate students.
Collaborations
Grants
Featured Publications presents a curated selection of the researcher’s most significant scientific contributions, reflecting their expertise, findings, and the broader impact of their work in advancing knowledge within their field.
Selected Publications
JCI Insight
Lysophosphatidic acid mediates skeletal muscle fibrosis in denervation via activation of YAP/TAZ
Skeletal Muscle
Dysregulated ATX-LPA and YAP/TAZ signaling in dystrophic Sgcd−/− mice with early fibrosis and inflammation
American Journal of Physiology
Matrix Biology
Involvement of lysophosphatidic acid-LPA1-YAP signaling in healthy and pathological FAPs migration
JCI Insight
Lysophosphatidic acid mediates skeletal muscle fibrosis in denervation via activation of YAP/TAZ

Meilyn Cruz-Soca, Adriana Córdova-Casanova, Jennifer Faundez-Contreras, Nicolás W. Martínez, Francesca Vaccaro-Rivera, Sebastián Bazaes-Astorga, Cristian Gutiérrez-Rojas, Felipe S. Gallardo, Daniela L. Rebolledo, Felipe A. Court, Jerold Chun, Carlos P. Vio, Soledad Matus, Juan Carlos Casar, Enrique Brandan
Skeletal Muscle
Dysregulated ATX-LPA and YAP/TAZ signaling in dystrophic Sgcd−/− mice with early fibrosis and inflammation
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Gutiérrez-Rojas, C., Córdova-Casanova, A., Faundez-Contreras, J., Cruz-Soca, M., Gallardo, F. S., Bock-Pereda, A., ... & Brandan, E
American Journal of Physiology
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Gallardo, F. S., Cruz-Soca, M., Bock-Pereda, A., Faundez-Contreras, J., Gutiérrez-Rojas, C., Gandin, A., ... & Brandan, E.
Matrix Biology
Involvement of lysophosphatidic acid-LPA1-YAP signaling in healthy and pathological FAPs migration

Bock-Pereda, A., Cruz-Soca, M., Gallardo, F. S., Córdova-Casanova, A., Gutierréz-Rojas, C., Faundez-Contreras, J., ... & Brandan, E.
JCI Insight

Skeletal Muscle
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American Journal of Physiology
%201_06_03%E2%80%AFp_m_.png)
Matrix Biology



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