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Tomás Pérez-Acle, PhD

Principal Investigator

Bioinspired Artificial Intelligence Lab (DLab)

Dr. Tomás Pérez-Acle is a computational biologist whose transdisciplinary research spans computational biophysics, neuromorphic AI, stochastic modeling, and the dynamics of complex biological networks. His recent work includes decoding retinal signals and exploring information as a modulator of human behavior. Over the past five years, he has published 20 Q1 articles and supervised six doctoral theses, supported by national and international funding sources such as FONDECYT, ANID, CORFO, the U.S. Air Force, and HP Labs.

He has held leadership roles at top Chilean institutions, including the Centro Interdisciplinario de Neurociencia de Valparaíso (CINV), the National Laboratory for High Performance Computing, and the Center for Mathematical Modeling. Currently, he is Principal Investigator and Director of Information and Communications Technology (ICT) at Fundación Ciencia & Vida and Director of the first PhD program in Computational Biology in Chile (USS).

Dr. Pérez-Acle contributes actively to science policy and evaluation panels (FONDECYT, FONDEF, CORFO), and has represented Chile internationally, such as in the Chile–USA Council on Science and Technology. During the COVID-19 pandemic, he joined expert advisory boards, providing modeling and communication to support public decision-making.

He is also an entrepreneur and cofounder of CONNECTOMICA SpA, a biotech startup developing therapies which target connexin channels in inflammatory diseases.

Grants

FONDECYT E-13240042 [2024-2028]: Collective Mind: from computational modeling to computational sociology. Unveiling the Role of Self and Situational Awareness in Agent-Based Systems (ABSs). (Principal Investigator) AFOSR FA9550-24-1-001 “Towards the Development of a Neuromorphic Visual System (NeViS): dissecting the encoding of the mammalian visual system using neuromorphic neural circuits” FONDECYT R-1211045 [2022-2025]: EXPLORING THE ROLE OF TRANSMEMBRANE VOLTAGE AND EXTRACELLULAR CA2+ ON THE THERMODYNAMIC EQUILIBRIUM BETWEEN THE OPEN AND CLOSED STATES OF THE HUMAN CX26 HEMICHANNEL. (Principal Investigator) FONDEF-ID21I10325 [2021-2023]: Desarrollo de una plataforma de inteligencia de datos (pid) para el nuevo sistema nacional de seguimiento ambiental. (Principal Investigator)

Collaborations

ECLIPSE Consortium | CDC NNaVi Project | Massey University FONDEF Plataforma inteligencia de datos PID ID21I10325 | FCV y Superintendencia del Medio

Selected Publications

Featured Publications presents a curated selection of the researcher’s most significant scientific contributions, reflecting their expertise, findings, and the broader impact of their work in advancing knowledge within their field.

Scientific Reports
Assessing the impact of misinformation during the spread of infectious diseases
Nature Methods
The need to implement FAIR principles in biomolecular simulations
Scientific Reports
Socioeconomic status correlates with COVID-19 vaccination coverage among primary and secondary students in the most populated city of Chile
Biological Research
Are we cultivating the perfect storm for a human avian influenza pandemic
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