Cancer is a group of life-threatening diseases characterized by the uncontrolled growth of abnormal cells in the body. Conventional oncology treatments are not curative in advanced stages of the disease and often result in severe adverse side effects. Cancer immunotherapy, which harnesses the ability of the immune system to eliminate cancer cells, has emerged as a new way to treat cancer patients with improved efficacy and fewer side effects. We are investigating how a specific type of immune cells, called T cells, can recognize and eliminate cancer cells to provide long-lasting protective immunity. Our research focuses on deciphering the molecular and cellular networks that underlie effective T cell-mediated immunity against solid tumors and metastases. Ultimately, we aim to use this knowledge to improve cancer immunotherapy in the future.